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Found 46 with Last Name = 'fustero' and Initial = 's'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi:  90nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  300nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  600nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  900nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  7.20E+3nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  9.30E+3nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi:  1.19E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  2.08E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  3.26E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi:  9.00E+4nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of jack bean alpha-mannosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046261(2-(3-Mercapto-5-methyl-hexanoylamino)-3-phenyl-pro...)
Affinity DataIC50:  41nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046258(3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...)
Affinity DataIC50:  50nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298107(3-(4-Hydroxy-phenyl)-2-(4,4,4-trifluoro-3-mercapto...)
Affinity DataIC50:  80nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298107(3-(4-Hydroxy-phenyl)-2-(4,4,4-trifluoro-3-mercapto...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298111(3-(4-Hydroxy-phenyl)-2-[3-phenyl-2-(4,4,4-trifluor...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50:  300nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298111(3-(4-Hydroxy-phenyl)-2-[3-phenyl-2-(4,4,4-trifluor...)
Affinity DataIC50:  430nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50:  580nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046258(3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046261(2-(3-Mercapto-5-methyl-hexanoylamino)-3-phenyl-pro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046261(2-(3-Mercapto-5-methyl-hexanoylamino)-3-phenyl-pro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298111(3-(4-Hydroxy-phenyl)-2-[3-phenyl-2-(4,4,4-trifluor...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298107(3-(4-Hydroxy-phenyl)-2-(4,4,4-trifluoro-3-mercapto...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed