TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human DYRK1A (129 to 509 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GSK3beta (1 to 433 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human GSK3beta (1 to 433 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human DYRK1A (129 to 509 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 301nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 315nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 352nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human ERG by Qpatch S8 assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG channel expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 5.64E+3nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch assayMore data for this Ligand-Target Pair
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human ERG by Qpatch S8 assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: >8.30E+3nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: >8.30E+3nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataIC50: >8.30E+3nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >8.90E+3nMAssay Description:Inhibition of CYP 1A2More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >8.90E+3nMAssay Description:Inhibition of CYP 1A2More data for this Ligand-Target Pair