BindingDB PrimarySearch_ki

Found 677 with Last Name = 'gong' and Initial = 'q'

Acetylcholinesterase(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50604668(CHEMBL5180947)

Ki: 0.400nMAssay Description:Mixed-type inhibition of AChE in mouse cerebral cortex using acetylthiocholine iodide as substrate by double reciprocal Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50078163(CHEMBL3417704)

Ki: <1nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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PC cid PC sid Similars

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)

Ki: <1nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Bcl-2-like protein 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)

Ki: <1nMAssay Description:Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50244168(CHEMBL4073496 | US10533010, Example I-239 | US1120...)

Ki: <1nMAssay Description:Inhibition of FITC-labeled BH3 peptide binding to human MCL1 expressed in Escherichia coli BL21 (DE3) incubated for 0.5 hrs by TR-FRET assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Acetylcholinesterase(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50585443(CHEMBL5082250)

Ki: 1.20nMAssay Description:Inhibition of mouse AChE assessed as inhibition constant using acetylthiocholine iodide as substrate measured every 2 mins by lineweaver-burk plot an...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581350(CHEMBL5079948)

Ki: <1.20nMAssay Description:Binding affinity to full length human MCL1 (173 to 321 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant incubated f...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Prothrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)

Ki: 4.5nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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CHEMBL MCE
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Prothrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50432209(BIBR-1048 | BIBR-1048-BS-RS1 | DABIGATRAN ETEXILAT...)

Ki: 4.5nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50303352(CHEMBL4164057)

Ki: 180nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from MCL1 (unknown origin) incubated for 2 hrs by fluorescence polarization-based competitive bin...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581323(CHEMBL5078508)

Ki: 320nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581344(CHEMBL5072573)

Ki: 360nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581345(CHEMBL5072266)

Ki: 360nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581320(CHEMBL5091070)

Ki: 370nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581321(CHEMBL5079372)

Ki: 420nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581351(CHEMBL5086378)

Ki: 490nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from MCL1 (unknown origin) incubated for 2 hrs by fluorescence polarization-based competitive bin...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581342(CHEMBL5077322)

Ki: 490nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581324(CHEMBL5080325)

Ki: 510nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50244168(CHEMBL4073496 | US10533010, Example I-239 | US1120...)

Ki: 576nMAssay Description:Inhibition of FITC-labeled BH3 peptide binding to Bcl-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 0.5 hrs by TR-FRET as...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581330(CHEMBL5088505)

Ki: 590nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581340(CHEMBL5091077)

Ki: 730nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581325(CHEMBL5078562)

Ki: 770nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581327(CHEMBL5076953)

Ki: 840nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581320(CHEMBL5091070)

Ki: 930nMAssay Description:Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581322(CHEMBL5079843)

Ki: 940nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581323(CHEMBL5078508)

Ki: 1.00E+3nMAssay Description:Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581329(CHEMBL5089281)

Ki: 1.40E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581321(CHEMBL5079372)

Ki: 1.50E+3nMAssay Description:Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581348(CHEMBL5092026)

Ki: 1.50E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581337(CHEMBL5090628)

Ki: 1.60E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581324(CHEMBL5080325)

Ki: 1.70E+3nMAssay Description:Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581322(CHEMBL5079843)

Ki: 1.70E+3nMAssay Description:Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581325(CHEMBL5078562)

Ki: 1.70E+3nMAssay Description:Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581326(CHEMBL5092439)

Ki: 2.10E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581328(CHEMBL5090868)

Ki: 2.10E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581326(CHEMBL5092439)

Ki: 2.40E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581320(CHEMBL5091070)

Ki: 2.60E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581330(CHEMBL5088505)

Ki: 2.90E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581322(CHEMBL5079843)

Ki: 3.60E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581321(CHEMBL5079372)

Ki: 3.90E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581334(CHEMBL5086158)

Ki: 4.30E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581323(CHEMBL5078508)

Ki: 4.60E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581339(CHEMBL5082559)

Ki: 4.60E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581329(CHEMBL5089281)

Ki: 4.60E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581326(CHEMBL5092439)

Ki: 4.90E+3nMAssay Description:Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581343(CHEMBL5086959)

Ki: 4.90E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581324(CHEMBL5080325)

Ki: 5.20E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581327(CHEMBL5076953)

Ki: 5.60E+3nMAssay Description:Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followe...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581332(CHEMBL5094724)

Ki: 5.90E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL

PNG

BDBM50581349(CHEMBL5080460)

Ki: 6.00E+3nMAssay Description:Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 677 total ) | Next | Last >>

Filter my 677 hits

Targets 29▿
- Acetylcholinesterase 236
- 5-hydroxytryptamine receptor 1A 78
- Cholinesterase 51
- Beta-secretase 1 44
- Sodium/hydrogen exchanger 1 42
- Carboxylic ester hydrolase 38
- Induced myeloid leukemia cell differentiation protein Mcl-1 36
- Sodium-dependent serotonin transporter 32
- Glycogen synthase kinase-3 beta 26
- Amine oxidase [flavin-containing] B 17
- Amine oxidase [flavin-containing] A 17
- Apoptosis regulator Bcl-2 17
- Bcl-2-like protein 1 13
- Potassium voltage-gated channel subfamily H member 2 5
- 5-hydroxytryptamine receptor 1B 3
- Sodium-dependent noradrenaline transporter 3
- Sodium-dependent dopamine transporter 3
- Matrix metalloproteinase-9 2
- Prothrombin 2
- Cytochrome P450 2C9 2
- Cytochrome P450 2D6 2
- Cytochrome P450 1A2 1
- Kelch-like ECH-associated protein 1 1
- Induced myeloid leukemia cell differentiation protein Mcl-1 homolog 1
- Cytochrome P450 2C19 1
- Protein P 1
- Cytochrome P450 2C8 1
- Cytochrome P450 3A4 1
- Cytochrome P450 2B6 1
- ...
Publications 13▿
- Eur J Med Chem 229: (2022) 206
- J Med Chem 64: 7483-7506 (2021) 78
- Eur J Med Chem 143: 33-47 (2018) 68
- J Med Chem 64: 10260-10285 (2021) 67
- Bioorg Med Chem 26: 3117-3125 (2018) 66
- J Med Chem 64: 1844-1855 (2021) 57
- Bioorg Med Chem 17: 1600-13 (2009) 57
- Eur J Med Chem 235: (2022) 30
- Eur J Med Chem 46: 4107-16 (2011) 25
- Bioorg Med Chem Lett 17: 2430-3 (2007) 17
- Bioorg Med Chem Lett 23: 2089-92 (2013) 1
- Eur J Med Chem 57: 21-8 (2012) 1
- Eur J Med Chem 144: 424-434 (2018) 1
Institutions 5▿
- East China University Of Science And Technology 340
- China Pharmaceutical University 152
- Chinese Academy Of Sciences 114
- Fudan University 67
- Xuzhou Medical University 1
Affinity: 0.068 to 2.4E+6 nM▿
- Ki 66
- IC50 521
- Kd 8
- EC50 82
- Affinity ≤ nM
Xtal structures: 13
Docked structures: 0
Catalog Cmpds: 23