Found 18 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50112086' 
Affinity DataKi: 4.5nMAssay Description:Inhibition of human thrombin using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibitory constant (Ki) was determined against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Inhibition of thrombin using S-2238 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human thrombin pre-incubated for 10 mins before Ac-FVR-AMC substrate addition and measured after 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured within 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured within 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human thrombin using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substrate preincubated for 10 mins by spectrophotometer anal...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human thrombin using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human thrombin-mediated platelet aggregation in cell-based assayMore data for this Ligand-Target Pair
