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Found 42 with Last Name = 'gordon' and Initial = 'td'
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286344(5-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataKi:  1nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286335((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-(3-...)
Affinity DataKi:  1nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286334((R)-N*4*-Hydroxy-N*1*-{(S)-2-(1H-indol-3-yl)-1-[5-...)
Affinity DataKi:  2nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286340((R)-N*1*-[(S)-1-(4-Benzyloxy-butylcarbamoyl)-2-(1H...)
Affinity DataKi:  2nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  2nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286337((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-(2-...)
Affinity DataKi:  2nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286347((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-(2-...)
Affinity DataKi:  3nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286349((R)-N*1*-[(S)-1-(3-Dimethylamino-propylcarbamoyl)-...)
Affinity DataKi:  3nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286345((R)-N*1*-[(S)-1-(4-Dimethylamino-butylcarbamoyl)-2...)
Affinity DataKi:  3nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286350((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-(2-...)
Affinity DataKi:  3nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286339((R)-N*1*-[(S)-1-(2-Ethylsulfanyl-ethylcarbamoyl)-2...)
Affinity DataKi:  3nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286346((R)-N*4*-Hydroxy-N*1*-{(S)-2-(1H-indol-3-yl)-1-[2-...)
Affinity DataKi:  4nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286343((R)-N*1*-[(S)-1-(4-Dimethylaminomethyl-benzylcarba...)
Affinity DataKi:  4nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286342((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-(2-...)
Affinity DataKi:  5nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286348((R)-N*1*-[(S)-1-[2-(2-Dimethylamino-ethylsulfanyl)...)
Affinity DataKi:  5nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286336((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-(2-...)
Affinity DataKi:  5nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286338((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-(2-...)
Affinity DataKi:  6nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)
Affinity DataKi:  6nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286341((R)-N*1*-[(S)-1-(2-Dimethylamino-ethylcarbamoyl)-2...)
Affinity DataKi:  12nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155144(4-(3-Phenyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155149(4-(3-Methyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155148((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50:  116nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155149(4-(3-Methyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155146(2-[6-(2-Morpholin-4-yl-ethoxy)-1H-indol-3-ylmethyl...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155147(2-[7-([1,4'']Bipiperidinyl-1''-carbonyl)-1H-indol-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155148((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2...)
Affinity DataIC50:  230nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155146(2-[6-(2-Morpholin-4-yl-ethoxy)-1H-indol-3-ylmethyl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50405583(CHEMBL5271785)
Affinity DataIC50:  306nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405584(CHEMBL5266620)
Affinity DataIC50:  364nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155145(4-(1H-Indol-2-ylmethylene)-5-pyrazin-2-yl-2,4-dihy...)
Affinity DataIC50:  410nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155144(4-(3-Phenyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50:  470nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50405587(CHEMBL5267979)
Affinity DataIC50:  475nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155147(2-[7-([1,4'']Bipiperidinyl-1''-carbonyl)-1H-indol-...)
Affinity DataIC50:  720nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155150(5-Cyclopropyl-4-[4-(2-diethylamino-ethyl)-3,5-dime...)
Affinity DataIC50:  840nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155150(5-Cyclopropyl-4-[4-(2-diethylamino-ethyl)-3,5-dime...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50405582(CHEMBL5280116)
Affinity DataIC50:  3.88E+3nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155145(4-(1H-Indol-2-ylmethylene)-5-pyrazin-2-yl-2,4-dihy...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50405586(CHEMBL5279578)
Affinity DataEC50:  37nMAssay Description:In vitro inhibitory activity against beta-2 adrenoceptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha contracted ...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405585(CHEMBL5286788)
Affinity DataEC50:  95nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...More data for this Ligand-Target Pair
In DepthDetails PubMed