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Found 36 with Last Name = 'green' and Initial = 'ai'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50234418((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Affinity DataKi:  10nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50234418((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340312((2,3-dichlorophenyl)(1-((4,4-difluoropiperidin-1-y...)
Affinity DataIC50:  0.300nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340311((3-fluoro-2-(trifluoromethyl)phenyl)(1-(morpholino...)
Affinity DataIC50:  0.700nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340313(1-((4,4-difluoropiperidin-1-yl)methyl)-N-(6-(trifl...)
Affinity DataIC50:  1.70nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340315(3-((4,4-difluoropiperidin-1-yl)methyl)-N-((1-(hydr...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340310((2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340316(3-cyclopropyl-N-(dicyclopropylmethyl)imidazo[1,5-a...)
Affinity DataIC50:  7nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340310((2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1...)
Affinity DataIC50:  11nMAssay Description:Agonist activity at rat CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340317(3-cyclopropyl-N-neopentylimidazo[1,5-a]pyridine-1-...)
Affinity DataIC50:  21nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340318((R)-3-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-y...)
Affinity DataIC50:  21nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340319(CHEMBL1760939 | N-((1-(hydroxymethyl)cyclopentyl)m...)
Affinity DataIC50:  33nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340321((R)-1-(4,4-difluoropiperidin-1-yl)-N-(3,3-dimethyl...)
Affinity DataIC50:  36nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340314(1-[(1,1-dioxidothiomorpholin-4-yl)methyl]-N-[6-(tr...)
Affinity DataIC50:  44nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340319(CHEMBL1760939 | N-((1-(hydroxymethyl)cyclopentyl)m...)
Affinity DataIC50:  58nMAssay Description:Agonist activity at rat CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340315(3-((4,4-difluoropiperidin-1-yl)methyl)-N-((1-(hydr...)
Affinity DataIC50:  68nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340323(1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-3-yl)et...)
Affinity DataIC50:  69nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340312((2,3-dichlorophenyl)(1-((4,4-difluoropiperidin-1-y...)
Affinity DataIC50:  90nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340320(1-(3,3-difluoropyrrolidin-1-yl)-N-((4-fluorophenyl...)
Affinity DataIC50:  92nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340322((R)-1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-y...)
Affinity DataIC50:  139nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340313(1-((4,4-difluoropiperidin-1-yl)methyl)-N-(6-(trifl...)
Affinity DataIC50:  347nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340318((R)-3-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-y...)
Affinity DataIC50:  705nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340310((2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1...)
Affinity DataIC50:  1.07E+3nMAssay Description:Agonist activity at rat CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340311((3-fluoro-2-(trifluoromethyl)phenyl)(1-(morpholino...)
Affinity DataIC50:  2.23E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340310((2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1...)
Affinity DataIC50:  2.57E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340314(1-[(1,1-dioxidothiomorpholin-4-yl)methyl]-N-[6-(tr...)
Affinity DataIC50:  1.27E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340319(CHEMBL1760939 | N-((1-(hydroxymethyl)cyclopentyl)m...)
Affinity DataIC50: >1.70E+4nMAssay Description:Agonist activity at rat CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340317(3-cyclopropyl-N-neopentylimidazo[1,5-a]pyridine-1-...)
Affinity DataIC50: >1.70E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340323(1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-3-yl)et...)
Affinity DataIC50: >1.70E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340322((R)-1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-y...)
Affinity DataIC50: >1.70E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340319(CHEMBL1760939 | N-((1-(hydroxymethyl)cyclopentyl)m...)
Affinity DataIC50: >1.70E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340320(1-(3,3-difluoropyrrolidin-1-yl)-N-((4-fluorophenyl...)
Affinity DataIC50: >1.70E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340321((R)-1-(4,4-difluoropiperidin-1-yl)-N-(3,3-dimethyl...)
Affinity DataIC50: >1.70E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340316(3-cyclopropyl-N-(dicyclopropylmethyl)imidazo[1,5-a...)
Affinity DataIC50: >1.70E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM172038(US10155002, Compound 44 | US10647700, Compound EPZ...)
Affinity DataEC50:  200nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50149904(CHEMBL3769963)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed