TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetCobra venom factor/Complement factor B/Complement factor D(Naja kaouthia (Monocled cobra) (Naja siamensis))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetCobra venom factor/Complement factor B/Complement factor D(Naja kaouthia (Monocled cobra) (Naja siamensis))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of purified TrkA cytoplasmic domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Target72 kDa type IV collagenase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant TIE2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Target72 kDa type IV collagenase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced maximum response after 1 hr by beta-galactosidase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetCobra venom factor/Complement factor B/Complement factor D(Naja kaouthia (Monocled cobra) (Naja siamensis))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human HDAC1 using rhodamine as substrate after 1 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetCobra venom factor/Complement factor B/Complement factor D(Naja kaouthia (Monocled cobra) (Naja siamensis))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
TargetCollagenase 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetCobra venom factor/Complement factor B/Complement factor D(Naja kaouthia (Monocled cobra) (Naja siamensis))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human HDAC2 using rhodamine as substrate after 1 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair