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Found 29 with Last Name = 'guillerm' and Initial = 'g'
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50370431(CHEMBL610574)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human placental AdoHcy hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM84862(5'-Deoxy-5'-thiodenosine scaffold, 6)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity for human placental S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50366808(CHEMBL603565)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity against S-Adenosyl-homocysteine hydrolase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85447(Epoxy analogue, I(a))
Affinity DataKi:  7.00E+3nM ΔG°:  -30.6kJ/mole IC50:  5.00E+4nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50366810(CHEMBL606109)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity against S-Adenosyl-homocysteine hydrolase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50369869(CHEMBL606446)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of purified recombinant human placental S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50369870(CHEMBL607985)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of purified recombinant human placental S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50370432(CHEMBL611108)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human placental AdoHcy hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50182453((E)-6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhom...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibitory activity against AdoHcy HydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50370433(CHEMBL610838)
Affinity DataKi:  1.90E+4nMAssay Description:Binding affinity for human placental S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50369871(CHEMBL140440)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibition of purified recombinant human placental S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50370435(CHEMBL610303)
Affinity DataKi:  5.00E+4nMAssay Description:Binding affinity for human placental S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1(Rattus norvegicus)
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50070637(CHEMBL295971 | L-2-amino-4-methoxy-cis-but-3-enoic...)
Affinity DataKi:  5.60E+4nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liverMore data for this Ligand-Target Pair
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85448(Epoxy analogue, I(b))
Affinity DataKi:  6.10E+4nM ΔG°:  -25.0kJ/mole IC50:  1.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50366809(CHEMBL604826)
Affinity DataKi:  6.70E+4nMAssay Description:Binding affinity against S-Adenosyl-homocysteine hydrolase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50370430(CHEMBL610300)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of human placental AdoHcy hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50370436(CHEMBL611107)
Affinity DataKi:  9.60E+4nMAssay Description:Binding affinity for human placental S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85450(Epithioamino acid analogue, II(a))
Affinity DataKi:  1.00E+5nM ΔG°:  -23.7kJ/mole IC50:  1.40E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85449(Epoxy analogue, I(c))
Affinity DataKi:  1.05E+5nM ΔG°:  -23.6kJ/mole IC50:  1.10E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50370434(CHEMBL610588)
Affinity DataKi:  1.05E+5nMAssay Description:Binding affinity for human placental S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85451(Epithioamino acid analogue, II(b))
Affinity DataKi:  1.40E+5nM ΔG°:  -22.9kJ/mole IC50:  3.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85452(Epithioamino acid analogue, II(c))
Affinity DataKi:  1.40E+5nM ΔG°:  -22.9kJ/mole IC50:  4.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50366378(CHEMBL604650)
Affinity DataKi:  1.66E+5nMAssay Description:Inhibitory constant against rat liver S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetS-adenosylmethionine synthase isoform type-1(Rattus norvegicus)
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50070638(1-AMINOCYCLOPENTANECARBOXYLIC ACID | 1-Amino-cyclo...)
Affinity DataKi:  5.16E+5nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1(Rattus norvegicus)
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50070635((R)-3-Amino-tetrahydro-furan-3-carboxylic acid | C...)
Affinity DataKi:  7.50E+5nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50370429(CHEMBL610573)
Affinity DataKi:  7.50E+5nMAssay Description:Inhibition of human placental AdoHcy hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1(Rattus norvegicus)
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50070634(4-Amino-tetrahydro-pyran-4-carboxylic acid | CHEMB...)
Affinity DataKi:  1.00E+6nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1(Rattus norvegicus)
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50070636((S)-3-Amino-tetrahydro-thiophene-3-carboxylic acid...)
Affinity DataKi:  1.04E+6nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1(Rattus norvegicus)
Umr 6519

Curated by ChEMBL
LigandPNGBDBM50070639(4-Amino-tetrahydro-thiopyran-4-carboxylic acid | C...)
Affinity DataKi:  3.00E+6nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant S-adenosyl L-Methionine synthetase (alpha-isoform) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed