Affinity DataKi: 2.70nMAssay Description:Inhibition of ERalpha in human MCF7 cellsMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Displacement of [125I]IMPY from human amyloid beta(1-42) aggregates incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University
Curated by ChEMBL
Banaras Hindu University
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition b...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Competitive inhibition of human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH as substrate preincubated for 60 mins followed by substrate addition by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University
Curated by ChEMBL
Banaras Hindu University
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Non-competitive inhibition of electric eel AChE using varying levels of acetylthiocholine iodide as substrate measured at 2 mins interval for 10 mins...More data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of human placental microsome aromatase using [1beta[3H]]androst-4-ene-3,17-dione as substrate after 15 mins in presence of NADPH by liquid...More data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 20 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute Of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 860nMAssay Description:Non-competitive inhibition of equine serum BuChE using varying levels of butyrylthiocholine iodide as substrate measured at 2 mins interval for 10 mi...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of ERbeta in human MCF7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate after 15 mins in presence of NADPH by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.59E+4nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of ERalpha in human MCF7 cells after 36 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0890nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of sulfatase (unknown origin) using 4-MUS as substrateMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University
Curated by ChEMBL
Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]DHEAS as substrate after 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Fluormone-ES2 binding affinity to ERalpha (unknown origin) after 2 hrs by fluorescent polarization based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of ERalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]DHEAS as substrate after 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of sulfatase (unknown origin) expressed in HEK293 cells using [3H]DHEAS as substrate after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH as substrate preincubated for 60 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH as substrate preincubated for 60 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University
Curated by ChEMBL
Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured for ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University
Curated by ChEMBL
Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University
Curated by ChEMBL
Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University
Curated by ChEMBL
Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured for ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of ERalpha (unknown origin) after 18 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair