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Found 111 with Last Name = 'hanestad' and Initial = 'k'
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326208(4-(4-Fluorophenyl)-N-(4-(3-(2-(methylamino)pyrimid...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326204(CHEMBL1243137 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326207(CHEMBL1243294 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50557717(CHEMBL4743666)
Affinity DataIC50:  28nMAssay Description:Inhibition of pig brain farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404039(CHEMBL5289941)
Affinity DataIC50:  32nMAssay Description:Inhibition of pig brain farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326202(CHEMBL1243042 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  56nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404036(CHEMBL5076091)
Affinity DataIC50:  61nMAssay Description:Inhibition of pig brain farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326198(CHEMBL1242977 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  66nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Mus musculus)TBA
LigandPNGBDBM50404035(CHEMBL5287177)
Affinity DataIC50:  77nMAssay Description:Inhibition of pig brain farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404000(CHEMBL5279604)
Affinity DataIC50:  80nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404034(CHEMBL5077043)
Affinity DataIC50:  81nMAssay Description:Inhibition of pig brain farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404037(CHEMBL5287302)
Affinity DataIC50:  90nMAssay Description:Inhibition of pig brain farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403677(CHEMBL5288088)
Affinity DataIC50:  92nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404035(CHEMBL5287177)
Affinity DataIC50:  96nMAssay Description:Inhibition of pig brain farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326205(CHEMBL1243167 | N-(2-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404033(CHEMBL5083562)
Affinity DataIC50:  135nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404030(CHEMBL5278809)
Affinity DataIC50:  140nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403999(CHEMBL5276902)
Affinity DataIC50:  165nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50404031(CHEMBL5270982)
Affinity DataIC50:  166nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326203(CHEMBL1243073 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  251nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403678(CHEMBL5276935)
Affinity DataIC50:  253nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403675(CHEMBL5081638)
Affinity DataIC50:  320nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326201(4-Chloro-N-(3-methyl-4-(3-(2-(methylamino)pyrimidi...)
Affinity DataIC50:  335nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403676(CHEMBL5284647)
Affinity DataIC50:  360nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326198(CHEMBL1242977 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  385nMAssay Description:Inhibition of LCK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403557(CHEMBL5084830)
Affinity DataIC50:  410nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326200(3-Chloro-N-(3-methyl-4-(3-(2-(methylamino)pyrimidi...)
Affinity DataIC50:  430nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326198(CHEMBL1242977 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  503nMAssay Description:Inhibition of Abl by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403553(CHEMBL5266739)
Affinity DataIC50:  520nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326209(CHEMBL1243108 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  542nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403674(CHEMBL5083490)
Affinity DataIC50:  580nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326198(CHEMBL1242977 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  630nMAssay Description:Inhibition of Tie-2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PLK1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of p70s6k by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JNK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of BTK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Jak3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CDK5 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Zap70 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of IGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EphB4 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CDK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CDK1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Erk1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PKBalpha by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Jak2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF18A(Homo sapiens)TBA
LigandPNGBDBM50403556(CHEMBL5287687)
Affinity DataIC50:  1.25E+3nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
In DepthDetails
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