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Found 1289 with Last Name = 'hansen' and Initial = 's'
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078280((R)-2-Cyano-N-[(R)-2-(2,5-difluoro-phenoxy)-1-meth...)
Affinity DataKi:  0.0200nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078281(2-Cyano-N-[(R)-2-(2,5-difluoro-phenoxy)-1-methyl-e...)
Affinity DataKi:  0.0420nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataKi:  0.0460nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC1 receptor expressed in BHK570 cells after 90 mins in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078284(CHEMBL38912 | N-[(R)-1-(4-Bromo-phenyl)-ethyl]-5-f...)
Affinity DataKi:  0.0470nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078290((R)-2-Cyano-N-[(R)-2-(2-fluoro-phenoxy)-1-methyl-e...)
Affinity DataKi:  0.0800nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389778(CHEMBL2070251)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078268((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.0850nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389773(CHEMBL2070246)
Affinity DataKi:  0.110nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078289((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389771(CHEMBL2070243)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389780(CHEMBL2069317)
Affinity DataKi:  0.130nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078272((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.170nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389777(CHEMBL2070250)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389776(CHEMBL2070249)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389774(CHEMBL2070247)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078271((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.220nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078269((R)-2-Cyano-N-[(R)-2-(3-fluoro-phenoxy)-1-methyl-e...)
Affinity DataKi:  0.240nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078282(2-Cyano-N-[2-(2-fluoro-phenoxy)-1-methyl-ethyl]-3,...)
Affinity DataKi:  0.240nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389769(BREMELANOTIDE)
Affinity DataKi:  0.25nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389779(CHEMBL2070252)
Affinity DataKi:  0.260nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389775(CHEMBL2070248)
Affinity DataKi:  0.330nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389783(CHEMBL2070245)
Affinity DataKi:  0.370nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078275((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.370nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078274((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.380nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078283(5-Fluoro-2-hydroxy-N-((R)-1-methyl-2-phenoxy-ethyl...)
Affinity DataKi:  0.440nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078277((R)-2-Cyano-N-[2-(3-fluoro-phenoxy)-1-methyl-ethyl...)
Affinity DataKi:  0.460nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389783(CHEMBL2070245)
Affinity DataKi:  0.470nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor human MC5 expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataKi:  0.480nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor human MC5 expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078294((R)-2-Cyano-3,3-dimethyl-N-((R)-1-methyl-2-phenoxy...)
Affinity DataKi:  0.580nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078294((R)-2-Cyano-3,3-dimethyl-N-((R)-1-methyl-2-phenoxy...)
Affinity DataKi:  0.580nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389782(CHEMBL2070374)
Affinity DataKi:  0.580nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304053(CHEMBL595677 | methyl 8-methyl-3-(4-(thiophen-3-yl...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant SERT expressed in african gree...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078286((S)-2-Cyano-N-[(R)-2-(2,5-difluoro-phenoxy)-1-meth...)
Affinity DataKi:  0.730nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataKi:  0.780nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078279((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  0.830nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304049(1-[3beta-(4-Chloro-phenyl)tropane-2beta-carbonyl-o...)
Affinity DataKi:  0.860nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant SERT expressed in african gree...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078293((R)-2-Cyano-N-[(R)-2-(2,3-difluoro-phenoxy)-1-meth...)
Affinity DataKi:  0.950nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389772(CHEMBL2070244)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304049(1-[3beta-(4-Chloro-phenyl)tropane-2beta-carbonyl-o...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389773(CHEMBL2070246)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor human MC5 expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC1 receptor expressed in BHK570 cells after 90 mins in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389771(CHEMBL2070243)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor human MC5 expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078288(2-Cyano-N-[(R)-2-(4-fluoro-phenoxy)-1-methyl-ethyl...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078270((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389783(CHEMBL2070245)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScytalone dehydratase(Magnaporthe grisea)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50078291((R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarb...)
Affinity DataKi:  2.20nMAssay Description:Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe griseaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389771(CHEMBL2070243)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304053(CHEMBL595677 | methyl 8-methyl-3-(4-(thiophen-3-yl...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304045(CHEMBL608703 | methyl 3-(4-chlorophenyl)-8-methyl-...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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