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Found 18 with Last Name = 'hebel' and Initial = 'd'
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataKi:  60nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-dihydroalprenolol from beta-1 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataKi:  120nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-dihydroalprenolol from beta-1 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataKi:  670nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-dihydroalprenolol from beta-1 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50279966(Azidothymidine difluoromethylenephosphonate deriva...)
Affinity DataKi:  2.23E+3nMAssay Description:Inhibitory constant was determined in an HIV-1 reverse transcriptase assay in which the [3H]dTTP concentration was varied (i.e. 40, 20, 10, 6, and 4 ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007478(4-(3-tert-Butylamino-2-hydroxy-propoxy)-5-fluoro-b...)
Affinity DataKi:  8.70E+4nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-dihydroalprenolol from beta-1 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50:  22nMAssay Description:Compound concentration that causes 50 % inhibition of HIV-1 peptide-derived reverse transcriptase (RT) obtained from HIV-1-infected H9 cell culturesMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50279966(Azidothymidine difluoromethylenephosphonate deriva...)
Affinity DataIC50:  620nMAssay Description:Compound concentration that causes 50 % inhibition of HIV-1 peptide-derived reverse transcriptase (RT)More data for this Ligand-Target Pair
In DepthDetails Article
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50279965(Azidothymidine difluoromethylenephosphonate deriva...)
Affinity DataIC50:  6.95E+3nMAssay Description:Compound concentration that causes 50 % inhibition of HIV-1 peptide-derived reverse transcriptase (RT)More data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataEC50:  7nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataEC50:  8.20nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataEC50:  9.20nMAssay Description:Activity was evaluated by measuring the inhibition of isolated hog H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataEC50:  38nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataEC50:  8.60nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataEC50:  130nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataEC50:  58nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataEC50:  6nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataEC50:  4.70nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007478(4-(3-tert-Butylamino-2-hydroxy-propoxy)-5-fluoro-b...)
Affinity DataEC50:  175nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed