BDBM50007477 4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-benzene-1,2-diol::CHEMBL10453

SMILES CC(C)(C)NCC(O)COc1ccc(O)c(O)c1F

InChI Key InChIKey=NBOURJIOPAPXKD-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007477   

TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataKi:  60nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-dihydroalprenolol from beta-1 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataEC50:  38nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataEC50:  9.20nMAssay Description:Activity was evaluated by measuring the inhibition of isolated hog H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataEC50:  8.60nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed