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Found 164 with Last Name = 'hedberg' and Initial = 'c'
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM23120(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50073975(1,1,1-Trifluoro-tridecan-2-one | 1,1,1-trifluorotr...)
Affinity DataKi:  140nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50073977(1,1,1-Trifluoro-nonan-2-one | 1,1,1-trifluorononan...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of rat intact neuron FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50244890(CHEMBL472535 | N-(2-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339874(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339873((S)-3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome FAAH assessed as reduction in 4-pyren-1-ylbutanoic acid release after 60 mins by reverse phase HPLC-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50244890(CHEMBL472535 | N-(2-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of rat brain membrane FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339876(6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339877(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339878((S)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339879((R)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339881(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339880(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339882((S)-3-(1-(2-amino-6-(benzofuran-2-yl)pyrimidin-4-y...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339883((S)-1-ethyl-3-(1-(2-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339884((S)-1-ethyl-3-(1-(4-(4-fluorophenyl)pyrimidin-2-yl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339879((R)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50244718(CHEMBL460273 | JNJ-1661010 | N-phenyl-4-(3-phenyl-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339885(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50161517(6-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-hexan-1-on...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373826(CHEMBL256470)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339874(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50:  18nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339878((S)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50161517(6-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-hexan-1-on...)
Affinity DataIC50:  25nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339873((S)-3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  26nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339889((S)-1-(1-(2-(benzofuran-2-yl)pyrimidin-4-yl)piperi...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339890((S)-1-(1-(2-(4-chlorophenyl)pyrimidin-4-yl)piperid...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339891((S)-1-ethyl-3-(1-(4-(thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339887(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339888(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339884((S)-1-ethyl-3-(1-(4-(4-fluorophenyl)pyrimidin-2-yl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373827(CHEMBL270865)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339876(6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...)
Affinity DataIC50:  36nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50:  39nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339892((S)-1-ethyl-3-(1-(2-p-tolylpyrimidin-4-yl)piperidi...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373831(CHEMBL272087)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  43nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50339894((S)-1-ethyl-3-(1-(2-(3-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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