Affinity DataKi: 6.20nMAssay Description:Inhibition of hexa-His-tagged JNK2 expressed in baculoviral system using GST-tagged cJun as substrate preincubated for 15 mins prior ATP addition mea...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 3.60E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 4.20E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 4.90E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 5.80E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 7.80E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of hexa-His-tagged JNK3 expressed in baculoviral system using GST-tagged cJun as substrate preincubated for 15 mins prior ATP addition mea...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of hexa-His-tagged JNK3 expressed in baculoviral system using GST-tagged cJun as substrate preincubated for 15 mins prior ATP addition mea...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of hexa-His-tagged JNK2 expressed in baculoviral system using GST-tagged cJun as substrate preincubated for 15 mins prior ATP addition mea...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of hexa-His-tagged JNK2 expressed in baculoviral system using GST-tagged cJun as substrate preincubated for 15 mins prior ATP addition mea...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair