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Found 214 with Last Name = 'hirata' and Initial = 'k'
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505559(CHEMBL4441303)
Affinity DataIC50:  0.0940nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505555(CHEMBL4447348)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505557(CHEMBL4527930)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505568(CHEMBL4482954)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505555(CHEMBL4447348)
Affinity DataIC50:  0.632nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505562(CHEMBL4445744)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505554(CHEMBL4564747)
Affinity DataIC50:  0.760nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505557(CHEMBL4527930)
Affinity DataIC50:  0.790nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505563(CHEMBL4527329)
Affinity DataIC50:  0.840nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505566(CHEMBL4582558)
Affinity DataIC50:  1nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505559(CHEMBL4441303)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505565(CHEMBL4474668)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505564(CHEMBL4527867)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505561(CHEMBL4475810)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505560(CHEMBL4471760)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505560(CHEMBL4471760)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505562(CHEMBL4445744)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505568(CHEMBL4482954)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505565(CHEMBL4474668)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505567(CHEMBL4457500)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505564(CHEMBL4527867)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505563(CHEMBL4527329)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505561(CHEMBL4475810)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505566(CHEMBL4582558)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337114(2'-((1R)-1-{(2R)-3-[2-Methyl-1-(naphthalen-2-yl)pr...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505554(CHEMBL4564747)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  5nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337116(2'-((1R)-1-{(2R)-3-[2-methyl-1-(naphthalen-2-yl)pr...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505567(CHEMBL4457500)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337113((RS)-2'-(1-{(2R)-3-[2-Methyl-1-(naphthalen-2-yl)pr...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337103(2'-((1R)-1-{(2R)-3-[1-(4-Chloro-3-fluorophenyl)-2-...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337112((RS)-3'-(1-{(2R)-3-[2-Methyl-1-(naphthalen-2-yl)pr...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337105((R)-1-((R)-cyclopropyl(2-(hydroxymethyl)phenyl)met...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337115(2'-((1R)-1-{(2R)-3-[1-(4-Chloro-3-fluorophenyl)-2-...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50320009((R)-1-((R)-cyclopropyl(o-tolyl)methoxy)-3-(2-methy...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50320009((R)-1-((R)-cyclopropyl(o-tolyl)methoxy)-3-(2-methy...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337104(3-[2-((1R)-1-{(2R)-2-Hydroxy-3-[2-methyl-1-(naphth...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50161093((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505558(CHEMBL4514842)
Affinity DataIC50:  37nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50320009((R)-1-((R)-cyclopropyl(o-tolyl)methoxy)-3-(2-methy...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50320018((2R)-1-(cyclopropyl(2-methoxyphenyl)methoxy)-3-(2-...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50320011((2R)-1-(cyclopropyl(phenyl)methoxy)-3-(2-methyl-1-...)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50320012((2R)-1-(cyclobutyl(phenyl)methoxy)-3-(2-methyl-1-(...)
Affinity DataIC50:  74nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505558(CHEMBL4514842)
Affinity DataIC50:  77nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50505556(CHEMBL4468530)
Affinity DataIC50:  81nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50320019((R)-1-((S)-cyclopropyl(o-tolyl)methoxy)-3-(2-methy...)
Affinity DataIC50:  83nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50319998((2R)-1-(2-methyl-1-(naphthalen-2-yl)propan-2-ylami...)
Affinity DataIC50:  92nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50320008((2R)-1-(1-(2-methoxyphenyl)ethoxy)-3-(2-methyl-1-(...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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