TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]NMS from human muscarinic acetylcholine receptor subtype 5 expressed in CHO cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 824nMAssay Description:Noncompetitive inhibition of human full length recombinant MMP13 using triple-helical fTHP-15 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.53E+3nMAssay Description:Noncompetitive inhibition of human full length recombinant MMP13 using triple-helical fTHP-15 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Noncompetitive inhibition of human full length recombinant MMP13 using triple-helical fTHP-15 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant MMP13 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Non-competitive inhibition of full-length recombinant human MMP-13 assessed as fTHP-15 substrate hydrolysisMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Displacement of [33P]sphingosine 1 phosphate from human S1P4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair