Compile Data Set for Download or QSAR
maximum 50k data
Found 194 with Last Name = 'hopper' and Initial = 'dw'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142842((S)-2-[(R)-Methoxycarbonyl-(6-methyl-naphthalen-2-...)
Affinity DataKi:  2.30nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142842((S)-2-[(R)-Methoxycarbonyl-(6-methyl-naphthalen-2-...)
Affinity DataKi:  2.30nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142858((S)-2-((R)-Methoxycarbonyl-naphthalen-2-yl-methyl)...)
Affinity DataKi:  2.5nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142858((S)-2-((R)-Methoxycarbonyl-naphthalen-2-yl-methyl)...)
Affinity DataKi:  2.5nMAssay Description:Ability to displace 0.4 nM [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142846((S)-2-[(R)-(6-Bromo-naphthalen-2-yl)-methoxycarbon...)
Affinity DataKi:  5.5nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142846((S)-2-[(R)-(6-Bromo-naphthalen-2-yl)-methoxycarbon...)
Affinity DataKi:  5.5nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142841((S)-2-[(R)-Methoxycarbonyl-(6-methoxy-naphthalen-2...)
Affinity DataKi:  245nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142841((S)-2-[(R)-Methoxycarbonyl-(6-methoxy-naphthalen-2...)
Affinity DataKi:  245nMAssay Description:Ability to displace 0.4 nM [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142856((R)-2-[(R)-(4-Chloro-phenyl)-methoxycarbonyl-methy...)
Affinity DataKi:  1.08E+3nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142855((S)-2-[(R)-(4-Chloro-phenyl)-methoxycarbonyl-methy...)
Affinity DataKi:  1.90E+3nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142847((R)-2-((S)-Methoxycarbonyl-naphthalen-2-yl-methyl)...)
Affinity DataKi:  2.02E+3nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142852((S)-2-[(R)-(4-Bromo-phenyl)-methoxycarbonyl-methyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142854((R)-2-((R)-Methoxycarbonyl-phenyl-methyl)-pyrrolid...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142848((R)-2-((R)-Methoxycarbonyl-p-tolyl-methyl)-pyrroli...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142850((S)-2-((R)-Methoxycarbonyl-phenyl-methyl)-pyrrolid...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50142860((S)-2-((R)-Methoxycarbonyl-p-tolyl-methyl)-pyrroli...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303103(1-(3-(3-(4-chloro-3-hydroxyphenyl)-2-(pyridin-4-yl...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303123(CHEMBL570681 | ethyl 3-(3-(7-fluoro-1H-indazol-4-y...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303098(5-(7-(8-azabicyclo[3.2.1]octan-3-yl)-2-(pyridin-4-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303121(CHEMBL585144 | ethyl 3-(3-(7-chloro-1H-indazol-4-y...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303100(2-chloro-5-(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303131(2-chloro-5-[13-(hydroxymethyl)-15-methyl-5-(pyridi...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303127(CHEMBL583133 | ethyl 3-(3-(7-methyl-1H-indazol-4-y...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303132(2-chloro-5-[13-(hydroxymethyl)-15-methyl-5-(pyridi...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303094(CHEMBL571129 | ethyl 3-(3-(3-hydroxyphenyl)-2-(pyr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259007((R)-2-(4'-((4-isobutyrylphenoxy)methyl)biphenyl-4-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259007((R)-2-(4'-((4-isobutyrylphenoxy)methyl)biphenyl-4-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303130(CHEMBL585148 | Methyl 6-(4-chloro-3-hydroxyphenyl)...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303110(CHEMBL585334 | ethyl 3-(3-(1H-indazol-4-yl)-2-(pyr...)
Affinity DataIC50:  2nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303111((2R)-1-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyr...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259009((R)-3-methyl-2-(4'-((5-oxo-5,6,7,8-tetrahydronapht...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50327157((R)-methyl 2-(3,4-dichlorophenyl)-2-((R)-piperidin...)
Affinity DataIC50:  2.70nMAssay Description:Potency of inhibiting 10 pM [125I]-RTI-55 binding to dopamine receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303102(5-(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-2-(py...)
Affinity DataIC50:  3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258875((R)-2-(4'-((4-(4-fluorobenzoyl)phenoxy)methyl)biph...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303124(7-(8-azabicyclo[3.2.1]octan-3-yl)-3-(7-fluoro-1H-i...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303097(3-(7-(8-azabicyclo[3.2.1]octan-3-yl)-2-(pyridin-4-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303122(3-(7-chloro-1H-indazol-4-yl)-7-(8-ethyl-8-azabicyc...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303125(CHEMBL571744 | ethyl 3-(2-(pyridin-4-yl)-3-(7-(tri...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303112(3-(1H-indazol-4-yl)-7-(8-(methylsulfonyl)-8-azabic...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258917((R)-2-(4'-((4-(cyclohexanecarbonyl)phenoxy)methyl)...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50327157((R)-methyl 2-(3,4-dichlorophenyl)-2-((R)-piperidin...)
Affinity DataIC50:  5.30nMAssay Description:Potency of inhibiting 10 pM [125I]-RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258875((R)-2-(4'-((4-(4-fluorobenzoyl)phenoxy)methyl)biph...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259009((R)-3-methyl-2-(4'-((5-oxo-5,6,7,8-tetrahydronapht...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303113(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dihydr...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303114(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dihydr...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303129(CHEMBL585335 | ethyl 3-(3-(1H-indazol-4-yl)-6-meth...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303096(7-(8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chloro-3-me...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303115(1-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dih...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319739(3,3-dimethyl-N-(4-(2-(4-sulfamoylphenylamino)pyrim...)
Affinity DataIC50:  10nMAssay Description:Inhibition of FLAG-tagged IKKbeta after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258917((R)-2-(4'-((4-(cyclohexanecarbonyl)phenoxy)methyl)...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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