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Found 1079 with Last Name = 'hunt' and Initial = 'kw'
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193676(US9670208, Example 295 4-(3-(cyclopropylmethyl)-[1...)
Affinity DataIC50:  0.400nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193385(US9670208, Example 57)
Affinity DataIC50:  0.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193773(US9670208, Example 402 4-(3-(4-fluorobenzyl)-[1,2,...)
Affinity DataIC50:  0.600nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350052(US10208024, Example 51 | US10766881, Example 51)
Affinity DataIC50:  0.600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350052(US10208024, Example 51 | US10766881, Example 51)
Affinity DataIC50:  0.600nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193675(US9670208, Example 279 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50:  0.600nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3 [397-806](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350059(US10208024, Example 58 | US10766881, Example 58)
Affinity DataIC50:  0.700nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350059(US10208024, Example 58 | US10766881, Example 58)
Affinity DataIC50:  0.700nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM191370(US9670208, Example 35)
Affinity DataIC50:  0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193381(US9670208, Example 49)
Affinity DataIC50:  0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193672(US9670208, Example 278 4-(3-(pyridin-2-ylmethyl)-[...)
Affinity DataIC50:  0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350042(US10208024, Example 41 | US10766881, Example 41)
Affinity DataIC50:  0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350042(US10208024, Example 41 | US10766881, Example 41)
Affinity DataIC50:  0.800nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193781(US9670208, Example 493 4-(3-((6-ethoxypyridin-3-yl...)
Affinity DataIC50:  0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350051(US10208024, Example 50 | US10766881, Example 50)
Affinity DataIC50:  0.900nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350051(US10208024, Example 50 | US10766881, Example 50)
Affinity DataIC50:  0.900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193756(US9670208, Example 317 4-(3-((4,4-difluorocyclohex...)
Affinity DataIC50:  0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193412(US9670208, Example 276 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50:  0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193396(US9670208, Example 121)
Affinity DataIC50:  0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193410(US9670208, Example 272 4-(3-((6-methoxypyridin-3-y...)
Affinity DataIC50:  0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193776(US9670208, Example 403 4-(3-(3-fluoro-4-methoxyben...)
Affinity DataIC50:  0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350049(6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3 [397-806](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350052(US10208024, Example 51 | US10766881, Example 51)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350049(6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...)
Affinity DataIC50:  1nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350052(US10208024, Example 51 | US10766881, Example 51)
Affinity DataIC50:  1nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350082(US10208024, Example 81 | US10766881, Example 81)
Affinity DataIC50:  1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350082(US10208024, Example 81 | US10766881, Example 81)
Affinity DataIC50:  1.10nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350033(US10208024, Example 32 | US10766881, Example 32)
Affinity DataIC50:  1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350050(6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...)
Affinity DataIC50:  1.30nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350050(6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...)
Affinity DataIC50:  1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350033(US10208024, Example 32 | US10766881, Example 32)
Affinity DataIC50:  1.30nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350032(US10208024, Example 31 | US10766881, Example 31)
Affinity DataIC50:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3 [397-806](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350049(6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...)
Affinity DataIC50:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350032(US10208024, Example 31 | US10766881, Example 31)
Affinity DataIC50:  1.40nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350049(6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...)
Affinity DataIC50:  1.40nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350045(US10208024, Example 44 | US10766881, Example 44)
Affinity DataIC50:  1.40nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350043(US10208024, Example 42 | US10766881, Example 42)
Affinity DataIC50:  1.40nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350045(US10208024, Example 44 | US10766881, Example 44)
Affinity DataIC50:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350043(US10208024, Example 42 | US10766881, Example 42)
Affinity DataIC50:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350061(US10208024, Example 60)
Affinity DataIC50:  1.5nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193411(US9670208, Example 275 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50:  1.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM462139(US10766881, Example 60)
Affinity DataIC50:  1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350048(US10208024, Example 47 | US10766881, Example 47)
Affinity DataIC50:  1.5nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3 [397-806](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350048(US10208024, Example 47 | US10766881, Example 47)
Affinity DataIC50:  1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350048(US10208024, Example 47 | US10766881, Example 47)
Affinity DataIC50:  1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350015(6-(3-amino-6-(1- methyl-1H-pyrazol-4- yl)pyrazin-2...)
Affinity DataIC50:  1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350044(US10208024, Example 43 | US10766881, Example 43)
Affinity DataIC50:  1.60nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350048(US10208024, Example 47 | US10766881, Example 47)
Affinity DataIC50:  1.60nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2 [403-822](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350044(US10208024, Example 43 | US10766881, Example 43)
Affinity DataIC50:  1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM350015(6-(3-amino-6-(1- methyl-1H-pyrazol-4- yl)pyrazin-2...)
Affinity DataIC50:  1.60nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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