TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10.8nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 18.4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of Taq DNA polymeraseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 62.6nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 76.2nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 83.4nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 84.8nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 92.3nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 189nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 226nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 237nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
Affinity DataIC50: 244nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 405nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 414nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 468nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
Affinity DataIC50: 572nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of Taq DNA polymeraseMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of topoisomerase II as conversion of catenated to decatenated KDNAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Taq DNA polymerase by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Taq DNA polymeraseMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Apparent telomerase inhibition by mixed mechanismMore data for this Ligand-Target Pair