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Found 240 with Last Name = 'inoue' and Initial = 'k'
TargetVasopressin V1a receptor(Microtus ochrogaster)
Emory University

Curated by ChEMBL
LigandPNGBDBM50380758(CHEMBL2017867)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]-LVA from prairie vole vasopressin V1A receptor after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Microtus ochrogaster)
Emory University

Curated by ChEMBL
LigandPNGBDBM50380759(CHEMBL2017869)
Affinity DataKi:  2.90nMAssay Description:Displacement of [125I]-OVTA from prairie vole Oxytocin receptor after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Microtus ochrogaster)
Emory University

Curated by ChEMBL
LigandPNGBDBM50380758(CHEMBL2017867)
Affinity DataKi:  3.60nMAssay Description:Displacement of [125I]-OVTA from prairie vole Oxytocin receptor after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Microtus ochrogaster)
Emory University

Curated by ChEMBL
LigandPNGBDBM50380757(CHEMBL2017868)
Affinity DataKi:  4.20nMAssay Description:Displacement of [125I]-OVTA from prairie vole Oxytocin receptor after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380757(CHEMBL2017868)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Microtus ochrogaster)
Emory University

Curated by ChEMBL
LigandPNGBDBM50380759(CHEMBL2017869)
Affinity DataKi:  9.40nMAssay Description:Displacement of [125I]-LVA from prairie vole vasopressin V1A receptor after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380758(CHEMBL2017867)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380759(CHEMBL2017869)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380759(CHEMBL2017869)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]Oxytocin from human OXTR expressed in CHO cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Microtus ochrogaster)
Emory University

Curated by ChEMBL
LigandPNGBDBM50380757(CHEMBL2017868)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]-LVA from prairie vole vasopressin V1A receptor after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50233853(CHEMBL3392901)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]Oxytocin from human OXTR expressed in CHO cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Microtus ochrogaster)
Emory University

Curated by ChEMBL
LigandPNGBDBM50380760(CHEMBL2017979)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-OVTA from prairie vole Oxytocin receptor after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380760(CHEMBL2017979)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380761(CHEMBL2017980)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Microtus ochrogaster)
Emory University

Curated by ChEMBL
LigandPNGBDBM50380760(CHEMBL2017979)
Affinity DataKi:  78nMAssay Description:Displacement of [125I]-LVA from prairie vole vasopressin V1A receptor after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380757(CHEMBL2017868)
Affinity DataKi:  530nMAssay Description:Displacement of [3H]-AVP from human V1A receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380757(CHEMBL2017868)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380758(CHEMBL2017867)
Affinity DataKi:  790nMAssay Description:Displacement of [3H]-AVP from human V1A receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380761(CHEMBL2017980)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-AVP from human V1A receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380758(CHEMBL2017867)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-AVP from human V1b receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380761(CHEMBL2017980)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-AVP from human V1b receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380761(CHEMBL2017980)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380760(CHEMBL2017979)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-AVP from human V1b receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380759(CHEMBL2017869)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-AVP from human V1b receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380758(CHEMBL2017867)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380759(CHEMBL2017869)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380760(CHEMBL2017979)
Affinity DataKi:  3.70E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380760(CHEMBL2017979)
Affinity DataKi:  4.80E+3nMAssay Description:Displacement of [3H]-AVP from human V1A receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380759(CHEMBL2017869)
Affinity DataKi:  8.70E+3nMAssay Description:Displacement of [3H]-AVP from human V1A receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50380757(CHEMBL2017868)
Affinity DataKi:  9.60E+3nMAssay Description:Displacement of [3H]-AVP from human V1b receptor after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366072(5-[4-[5-(2-Methoxybenzyl)-1H-tetrazol-1-yl]phenyl]...)
Affinity DataIC50:  25nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366073(5-[4-[5-(2-Hydroxybenzyl)-1H-tetrazol-1-yl]phenyl]...)
Affinity DataIC50:  37nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366069(US9873683, Example 79)
Affinity DataIC50:  39nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366075(5-[4-(5-Phenethyl-1H-tetrazol-1-yl)phenyl]-1H-naph...)
Affinity DataIC50:  44nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50391931(CHEMBL2147632)
Affinity DataIC50:  50.1nMAssay Description:Inhibition of human BChE after 30 mins by microplate reader methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50391931(CHEMBL2147632)
Affinity DataIC50:  50.1nMAssay Description:Inhibition of human BChE after 30 mins by microplate reader methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM365870(US9873683, Example 31)
Affinity DataIC50:  51nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366062(US9873683, Example 67)
Affinity DataIC50:  53nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366049(US9873683, Example 43)
Affinity DataIC50:  53nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50391933(CHEMBL2147631)
Affinity DataIC50:  61.2nMAssay Description:Inhibition of human BChE after 30 mins by microplate reader methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM393615(US09969700, 173)
Affinity DataIC50:  64nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366057(US9873683, Example 61)
Affinity DataIC50:  74nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366078(5-[6-[5-(2-Hydroxybenzyl)-1H-tetrazol-1-yl]pyridin...)
Affinity DataIC50:  77nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM365827(US9873683, Example 27)
Affinity DataIC50:  78nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366077(5-[4-(2-Phenethyl-1H-imidazol-1-yl)phenyl]-1H-naph...)
Affinity DataIC50:  78nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM365950(US9873683, Example 37)
Affinity DataIC50:  79nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM365816(US9873683, Example 25)
Affinity DataIC50:  82nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366071(US9873683, Example 83)
Affinity DataIC50:  87nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM366058(US9873683, Example 62)
Affinity DataIC50:  88nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM365756(US9873683, Example 22)
Affinity DataIC50:  91nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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