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Found 3142 with Last Name = 'ito' and Initial = 'a'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346374(3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...)
Affinity DataKi:  0.000178nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50359960(CHEMBL1927094)
Affinity DataKi:  0.000185nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50359961(CHEMBL1927095)
Affinity DataKi:  0.000778nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataKi:  0.00157nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50359962(CHEMBL1927096)
Affinity DataKi:  0.0161nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021919(CHEMBL3298595)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021919(CHEMBL3298595)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M1 receptor in cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021919(CHEMBL3298595)
Affinity DataKi:  0.0270nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M2 receptor in heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420815(CHEMBL2088054)
Affinity DataKi:  0.0373nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50316964(CHEMBL1086961 | N'-cyano-N-(3-(4-(pyridin-2-yl)pip...)
Affinity DataKi:  0.0380nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat brain cortex after 30 mins liquid scintillation spectrometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021928(CHEMBL3298599)
Affinity DataKi:  0.0410nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M1 receptor in cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021928(CHEMBL3298599)
Affinity DataKi:  0.0490nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021928(CHEMBL3298599)
Affinity DataKi:  0.0530nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M2 receptor in heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021922(CHEMBL3298596)
Affinity DataKi:  0.0550nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M1 receptor in cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021904(CHEMBL3298588)
Affinity DataKi:  0.0560nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021922(CHEMBL3298596)
Affinity DataKi:  0.0640nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004193(CHEMBL3236476)
Affinity DataKi:  0.0648nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420812(CHEMBL2088061)
Affinity DataKi:  0.0672nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004180(CHEMBL3236474)
Affinity DataKi:  0.0711nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021935(CHEMBL3298600)
Affinity DataKi:  0.0730nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M1 receptor in cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50359955(CHEMBL1927089)
Affinity DataKi:  0.0842nMAssay Description:Displacement of [3H]-8-OH-DPAT from Sprague-Dawley rat brain cortex serotonin 5-HT1A receptor after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420804(CHEMBL2088055)
Affinity DataKi:  0.0892nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50400866(CHEMBL2204348)
Affinity DataKi:  0.0902nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004195(CHEMBL3236478)
Affinity DataKi:  0.0908nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004175(CHEMBL3236486)
Affinity DataKi:  0.0916nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004196(CHEMBL3236479)
Affinity DataKi:  0.0939nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021904(CHEMBL3298588)
Affinity DataKi:  0.0950nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M1 receptor in cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004181(CHEMBL3236475)
Affinity DataKi:  0.0954nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004174(CHEMBL3236485)
Affinity DataKi:  0.0970nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021935(CHEMBL3298600)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50516776(CHEMBL4437741)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004176(CHEMBL3236487)
Affinity DataKi:  0.105nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50400874(CHEMBL2086410)
Affinity DataKi:  0.106nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045494(CHEMBL3310115)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50516789(CHEMBL4559193)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50118178(CHEMBL3613172)
Affinity DataKi:  0.113nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004173(CHEMBL3236484)
Affinity DataKi:  0.114nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420810(CHEMBL2088060)
Affinity DataKi:  0.114nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021938(CHEMBL3298763)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021938(CHEMBL3298763)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M1 receptor in cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021922(CHEMBL3298596)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M2 receptor in heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50021893(CHEMBL3298333)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004194(CHEMBL3236477)
Affinity DataKi:  0.122nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420816(CHEMBL2088053)
Affinity DataKi:  0.124nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420814(CHEMBL2088056)
Affinity DataKi:  0.127nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420803(CHEMBL2088057)
Affinity DataKi:  0.134nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50118191(CHEMBL3613173)
Affinity DataKi:  0.136nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50400873(CHEMBL2088029)
Affinity DataKi:  0.137nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004179(CHEMBL3236473)
Affinity DataKi:  0.139nMAssay Description:Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50344285(CHEMBL1779047 | quinuclidin-4-yl biphenyl-2-ylcarb...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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