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Found 165 with Last Name = 'jayaraman' and Initial = 'm'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102589(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102564(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  0.760nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353767(CHEMBL1829430)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353767(CHEMBL1829430)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  1.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  1.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102577(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102577(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50076050(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  1.16nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102565(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  1.19nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102565(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  1.19nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  2.47nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  2.47nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102578(7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102578(7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50090971(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  2.94nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353799(CHEMBL1829424)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353799(CHEMBL1829424)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353767(CHEMBL1829430)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102564(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  3.04nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353820(CHEMBL1829432)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  5.95nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50063324(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataIC50:  5.95nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102571(3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  6.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102571(3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  6.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102581(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  7.37nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102572(6-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102572(6-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353799(CHEMBL1829424)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353821(CHEMBL1829246)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353823(CHEMBL1829422)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102589(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353822(CHEMBL1829431)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102583(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  19.4nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353760(CHEMBL1829248)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353761(CHEMBL1829406)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353762(CHEMBL1829423)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353763(CHEMBL1829401)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353764(CHEMBL1829420)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102579(3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  33.2nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102572(6-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  34.2nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102572(6-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  34.2nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353765(CHEMBL1829418)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102580(7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  45nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102565(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  48nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353766(CHEMBL1829399)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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