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Found 73 with Last Name = 'jiao' and Initial = 'j'
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50480998(CHEMBL567972)
Affinity DataIC50:  300nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481005(CHEMBL568586)
Affinity DataIC50:  400nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  500nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308316((S)-Benzyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-(phe...)
Affinity DataIC50:  580nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50480995(CHEMBL570280)
Affinity DataIC50:  600nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481012(CHEMBL570499)
Affinity DataIC50:  700nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481007(CHEMBL568184)
Affinity DataIC50:  800nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481011(CHEMBL571358)
Affinity DataIC50:  900nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308290((S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308307((S)-7-(2-(Hydroxyamino)-2-oxoethoxy)-N-(naphthalen...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50475234(CHEMBL189912)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308300((S)-tert-Butyl 3-(3-chlorophenylcarbamoyl)-7-(2-(h...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50480996(CHEMBL568185)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308284((S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50480994(CHEMBL586060)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481010(CHEMBL570279)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308304((S)-tert-Butyl 3-(3-chloro-4-fluorophenylcarbamoyl...)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481001(CHEMBL578209)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50480993(CHEMBL567155)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308292((S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481009(CHEMBL571802)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308296((S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481002(CHEMBL585905)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308308((S)-tert-Butyl 3-(biphenyl-4-ylcarbamoyl)-7-(2-(hy...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481004(CHEMBL576109)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308309((S)-N-(Biphenyl-4-yl)-7-(2-(hydroxyamino)-2-oxoeth...)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308298((S)-tert-Butyl 3-(4-fluorophenylcarbamoyl)-7-(2-(h...)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481006(CHEMBL570492)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308288((S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-...)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50480997(CHEMBL566697)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481000(CHEMBL568886)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308310((S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-...)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308301((S)-N-(3-chlorophenyl)-7-(2-(hydroxyamino)-2-oxoet...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308299((S)-N-(4-Fluorophenyl)-7-(2-(hydroxyamino)-2-oxoet...)
Affinity DataIC50:  3.23E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50480999(CHEMBL570050)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308305((S)-N-(3-Chloro-4-fluorophenyl)-7-(2-(hydroxyamino...)
Affinity DataIC50:  3.34E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308303((S)-N-(2,4-Dimethylphenyl)-7-(2-(hydroxyamino)-2-o...)
Affinity DataIC50:  3.39E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM232987((E)-3-(4-(4-methoxybenzyloxy)-3-methoxyphenyl)-N-h...)
Affinity DataIC50:  3.40E+3nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308286((S)-tert-Butyl 3-(benzylcarbamoyl)-7-(2-(hydroxyam...)
Affinity DataIC50:  3.41E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308311((S)-7-(2-(Hydroxyamino)-2-oxoethoxy)-N-pentyl-1,2,...)
Affinity DataIC50:  3.54E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308297((S)-7-(2-(Hydroxyamino)-2-oxoethoxy)-N-m-tolyl-1,2...)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308302((S)-tert-Butyl 3-(2, 4-dimethylphenylcarbamoyl)-7-...)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308293((S)-7-(2-(Hydroxyamino)-2-oxoethoxy)-N-p-tolyl-1,2...)
Affinity DataIC50:  3.82E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481003(CHEMBL567971)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308294((S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50481008(CHEMBL583409)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308289((S)-7-(2-(Hydroxyamino)-2-oxoethoxy)-N-phenethyl-1...)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308295((S)-7-(2-(Hydroxyamino)-2-oxoethoxy)-N-o-tolyl-1,2...)
Affinity DataIC50:  4.13E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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