Compile Data Set for Download or QSAR
maximum 50k data
Found 266 with Last Name = 'jorgensen' and Initial = 'wt'
TargetOxytocin receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)
Affinity DataKi:  0.800nMAssay Description:Agonist activity at human oxytocin receptor expressed in HEK293 cells assessed as increase in IP1 accumulation preincubated for 1 hr followed by addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50170660(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Affinity DataKi:  1.03nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334458(CHEMBL1643901 | N-(3-Fluorobenzyl)-N-methyl-8-amin...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in HEK cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50026948((trans) [3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344628(CHEMBL1779060 | N-(2-(2-methoxy-5-methylbenzamido)...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50175145(8-(2-aminoethyl)-N-(bis(4-fluorophenyl)methyl)-8-a...)
Affinity DataKi:  12.5nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334461(2-butyl-3-(4-chlorophenyl)-1-azabicyclo[2.2.2]oct-...)
Affinity DataKi:  14nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334459((1S,2S,3S,5R)-methyl 8-(3-iodoallyl)-3-p-tolyl-8-a...)
Affinity DataKi:  17nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334455(CHEMBL1643900 | N-(2-(3'-Fluorophenyl)ethyl)-8-ami...)
Affinity DataKi:  19nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344629(CHEMBL1779059 | N-(2-(4-methoxy-3-phenethoxyphenyl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139178(CHEMBL3763342)
Affinity DataKi:  27nMAssay Description:Agonist activity at human oxytocin receptor expressed in HEK293 cells assessed as increase in IP1 accumulation preincubated for 1 hr followed by addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139178(CHEMBL3763342)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50026948((trans) [3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct...)
Affinity DataKi:  44nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]SCH233930 from human D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50026948((trans) [3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct...)
Affinity DataKi:  57nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139178(CHEMBL3763342)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin 1a receptor expressed in HEK293 cells after 90 mins by microbeta 2 microplate-reader methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139179(CHEMBL3763951)
Affinity DataKi:  62nMAssay Description:Agonist activity at human oxytocin receptor expressed in HEK293 cells assessed as increase in IP1 accumulation preincubated for 1 hr followed by addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139179(CHEMBL3763951)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139373(CHEMBL3763823)
Affinity DataKi:  64nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cells assessed as inhibition of vasopressin induced IP1 accumulation pretrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139373(CHEMBL3763823)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(CHEMBL1643902 | N-(2-(3'-Fluorophenyl)ethyl)-N-met...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in HEK cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139178(CHEMBL3763342)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin 1a receptor expressed in HEK293 cells after 90 mins by microbeta 2 microplate-reader methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139183(CHEMBL3763217)
Affinity DataKi:  130nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cells assessed as inhibition of vasopressin induced IP1 accumulation pretrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139176(CHEMBL3763174)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139176(CHEMBL3763174)
Affinity DataKi:  195nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cells assessed as inhibition of vasopressin induced IP1 accumulation pretrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334457(CHEMBL1643899 | N-(3-Fluorobenzyl)-8-aminopentacyc...)
Affinity DataKi:  198nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139178(CHEMBL3763342)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]-oxytocin from human OTR expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139178(CHEMBL3763342)
Affinity DataKi:  230nMAssay Description:Agonist activity at human oxytocin receptor expressed in HEK293 cells assessed as increase in IP1 accumulation preincubated for 1 hr followed by addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139177(CHEMBL3765689)
Affinity DataKi:  248nMAssay Description:Agonist activity at human oxytocin receptor expressed in HEK293 cells assessed as increase in IP1 accumulation preincubated for 1 hr followed by addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50283980(CHEMBL4166008)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139146(CHEMBL3765356)
Affinity DataKi:  266nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cells assessed as inhibition of vasopressin induced IP1 accumulation pretrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139138(CHEMBL3763620)
Affinity DataKi:  409nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cells assessed as inhibition of vasopressin induced IP1 accumulation pretrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139182(CHEMBL3765525)
Affinity DataKi:  449nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin 1a receptor expressed in HEK293 cells after 90 mins by microbeta 2 microplate-reader methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139180(CHEMBL3764572)
Affinity DataKi:  466nMAssay Description:Displacement of [3H]-oxytocin from human oxytocin receptor expressed in HEK293 cells after 90 mins by microbeta 2 microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334459((1S,2S,3S,5R)-methyl 8-(3-iodoallyl)-3-p-tolyl-8-a...)
Affinity DataKi:  500nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50283972(CHEMBL4162565)
Affinity DataKi:  643nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334455(CHEMBL1643900 | N-(2-(3'-Fluorophenyl)ethyl)-8-ami...)
Affinity DataKi:  705nMAssay Description:Inhibition of muscarinic M4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50283952(CHEMBL4173250)
Affinity DataKi:  795nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139179(CHEMBL3763951)
Affinity DataKi:  801nMAssay Description:Displacement of [3H]-oxytocin from human OTR expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50139179(CHEMBL3763951)
Affinity DataKi:  801nMAssay Description:Antagonist activity at human vasopressin 1a receptor expressed in HEK293 cells assessed as inhibition of vasopressin induced IP1 accumulation pretrea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50283978(CHEMBL4176616)
Affinity DataKi:  874nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334459((1S,2S,3S,5R)-methyl 8-(3-iodoallyl)-3-p-tolyl-8-a...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 266 total ) | Next | Last >>
Jump to: