TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Compound was tested for 50% inhibitory concentration that was required for irreversible inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Compound was evaluated for the inhibition of Rat kidney Aldehyde reductase (RKALR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Compound was evaluated for the inhibition of Rat Lens Aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Compound was evaluated for the inhibition of Rat Lens Aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Compound was evaluated for the inhibition of Rat Lens Aldose reductase (RLAR)More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 8More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase (HPAR).More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity of the compound against rat lens aldose reductase (RLAR).More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity of the compound against rat lens aldose reductase (RLAR).More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity of the compound against rat lens aldose reductase (RLAR).More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 8More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity of the compound against rat lens aldose reductase (RLAR).More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase (HPAR)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at time 2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Compound was tested for 50% inhibitory concentration that was required for irreversible inhibition of aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in 30 -70% (NH4)2SO4.More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at at time 2More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase (HPAR)More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in 30 -70% (NH4)2SO4.More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 1More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 8More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase (HPAR)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in 30 -70% (NH4)2SO4.More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:Compound was evaluated for the inhibition of Rat kidney Aldehyde reductase (RKALR)More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at time 1More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Compound was evaluated for the inhibition of Rat kidney Aldehyde reductase (RKALR)More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at at time 2More data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 1More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 8More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Compound was evaluated for the inhibition of Rat kidney Aldehyde reductase (RKALR)More data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 8More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Compound was evaluated for the inhibition of Rat Lens Aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute
Curated by ChEMBL
National Eye Institute
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was tested for 50% inhibitory concentration that was required for irreversible inhibition of aldose reductaseMore data for this Ligand-Target Pair