Affinity DataKi: 0.0851nMAssay Description:Binding affinity towards histamine H3 receptor using [3H](R)-alpha-methylhistamine as radioligand in guinea pig cortical homogenatesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.145nMAssay Description:Binding affinity towards histamine H3 receptor using [3H](R)-alpha-methylhistamine as radioligand in guinea pig cortical homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 0.151nMAssay Description:Binding affinity towards histamine H3 receptor using [3H](R)-alpha-methylhistamine as radioligand in guinea pig ileum LMMP homogenatesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.660nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.741nMAssay Description:In vitro inhibitory activity against Cholecystokinin type B receptor using [125I]BH-CCK-8S as radioligand in mouse cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.780nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.830nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity towards histamine H3 receptor using [3H](R)-alpha-methylhistamine as radioligand in guinea pig cortical homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of 20 pM [125I]BH-CCK-8S binding to mouse cortical membrane Cholecystokinin 2 receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of binding of [125I]CCK-8S to Cholecystokinin type B receptor in mouse cerebral cortex homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:In vitro inhibitory activity against Cholecystokinin type B receptor using [125I]BH-CCK-8S as radioligand in mouse cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:In vitro inhibitory activity against Cholecystokinin type B receptor using [125I]BH-CCK-8S as radioligand in mouse cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:In vitro inhibitory activity against Cholecystokinin type B receptor using [125I]BH-CCK-8S as radioligand in mouse cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro inhibitory activity against Cholecystokinin type B receptor using [125I]BH-CCK-8S as radioligand in mouse cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of 20 pM [125I]BH-CCK-8S binding to mouse cortical membrane Cholecystokinin 2 receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Ability to displace [3H]R-alpha-methylhistamine from histamine H3 receptor in guinea pig ileum longitudinal muscle myenteric plexus(LMMP) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Ability to displace [3H]R-alpha-methylhistamine from histamine H3 receptor in guinea pig ileum longitudinal muscle myenteric plexus(LMMP) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Competition with 20 pM [125I]BH-CCK-8S for Cholecystokinin type B receptor binding sites in mouse cortical homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Competition with 20 pM [125I]BH-CCK-8S for Cholecystokinin type B receptor binding sites in mouse cortical homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [125I]BH-CCK8-8S from CCK2 receptor in canine gastric mucosaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Ability to displace [3H]R-alpha-methylhistamine from histamine H3 receptor in guinea pig ileum longitudinal muscle myenteric plexus(LMMP) membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Competition with 20 pM [125I]BH-CCK-8S for Cholecystokinin type B receptor binding sites in mouse cortical homogenatesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Ability to displace [3H]R-alpha-methylhistamine from histamine H3 receptor in guinea pig ileum longitudinal muscle myenteric plexus(LMMP) membranesMore data for this Ligand-Target Pair