Found 274 with Last Name = 'kaszubska' and Initial = 'w' TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibitory constant of the compound was determined against Protein-tyrosine phosphatase 1B (PTB1B)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Inhibitory constant of compound against T cell protein tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 920nM ΔG°: -34.1kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
3D Structure (crystal)TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 2.10E+3nM ΔG°: -32.1kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 5.70E+3nMAssay Description:Binding affinity of the compound was determined against protein tyrosine phosphatase PTB1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 6.90E+3nM ΔG°: -29.2kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 1.15E+4nM ΔG°: -27.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
Affinity DataKi: 1.92E+4nM ΔG°: -26.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 2.30E+4nM ΔG°: -26.2kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-25.6kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 6.03E+4nM ΔG°: -23.8kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 1.22E+5nM ΔG°: -22.1kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 1.48E+5nMAssay Description:Binding affinity of the compound was determined against protein tyrosine phosphatase PTB1BMore data for this Ligand-Target Pair
Affinity DataKi: 1.64E+5nMAssay Description:Inhibitory activity of the compound was determined against T cell protein tyrosine phosphatase (TCPTP)More data for this Ligand-Target Pair
Affinity DataKi: 1.64E+5nM ΔG°: -21.4kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2.02E+5nMAssay Description:Inhibitory constant of compound against T cell protein tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 2.16E+5nM ΔG°: -20.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 6.34E+5nMAssay Description:Inhibitory constant of compound against T cell protein tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nM EC50: 5.80nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nM EC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nM EC50: 16nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nM EC50: 85nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nM EC50: 10nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nM EC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to GHSRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nM EC50: 45nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nM EC50: 19nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nM EC50: 97nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nM EC50: 32nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nM EC50: 11nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nM EC50: 42nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of binding to human growth hormone secretagogue receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
