Compile Data Set for Download or QSAR
maximum 50k data
Found 720 with Last Name = 'kelly' and Initial = 'r'
LigandPNGBDBM50514220(CHEMBL4535151 | US11274105, Example 188)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514222(CHEMBL4580244 | US11274105, Example 193)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514203(CHEMBL4593361 | US11274105, Example 6)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514196(CHEMBL4476472)
Affinity DataKi:  0.0510nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514202(CHEMBL4446369 | US11274105, Example 179)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
LigandPNGBDBM50514199(CHEMBL4553660 | US11274105, Example 182)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514200(CHEMBL4446378 | US10703733, Comparative Example 1)
Affinity DataKi:  0.0760nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
LigandPNGBDBM50514215(CHEMBL4577379 | US11274105, Example 4)
Affinity DataKi:  0.0900nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514201(CHEMBL4547370 | US11274105, Example 191)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514214(CHEMBL4542646 | US11274105, Example 41)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514206(CHEMBL4588330 | US11274105, Example 187)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514219(CHEMBL4438074 | US11274105, Example 181)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514216(CHEMBL4528051 | US11274105, Example 5)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514218(CHEMBL4539543 | US11274105, Example 197)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514204(CHEMBL4437832)
Affinity DataKi:  0.110nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514217(CHEMBL4452794 | US11274105, Example 196)
Affinity DataKi:  0.200nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514208(CHEMBL4469850 | US11274105, Example 61)
Affinity DataKi:  0.280nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514207(CHEMBL4562159)
Affinity DataKi:  0.370nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514197(CHEMBL4561691 | US11274105, Example 63)
Affinity DataKi:  0.5nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514205(CHEMBL4452403)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514209(CHEMBL4460664)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Iubo-Ag)

Curated by ChEMBL
LigandPNGBDBM5566(2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidin...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Iubo-Ag)

Curated by ChEMBL
LigandPNGBDBM5566(2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidin...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116067((Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)...)
Affinity DataKi:  5.30E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226485((R)-3-(3-fluoro-4-(tetrahydro-2H-pyran-4-yl)phenyl...)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226479((R)-3-(3,5-difluoro-4-morpholinophenyl)-2-oxooxazo...)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226484((5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl...)
Affinity DataKi:  1.05E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226480((R)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidi...)
Affinity DataKi:  1.46E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226481((5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl...)
Affinity DataKi:  2.93E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226482((5R)-3-[3,5-difluoro-4-(1-oxidotetrahydro-2H-thiop...)
Affinity DataKi:  3.55E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50514220(CHEMBL4535151 | US11274105, Example 188)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514199(CHEMBL4553660 | US11274105, Example 182)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514222(CHEMBL4580244 | US11274105, Example 193)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514200(CHEMBL4446378 | US10703733, Comparative Example 1)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
LigandPNGBDBM50514224(CHEMBL4464768)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514218(CHEMBL4539543 | US11274105, Example 197)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514202(CHEMBL4446369 | US11274105, Example 179)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
LigandPNGBDBM50514216(CHEMBL4528051 | US11274105, Example 5)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514219(CHEMBL4438074 | US11274105, Example 181)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50557972(CHEMBL4790186)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant full length N-terminal polyHis-tagged PI3K p110delta/p85alpha (unknown origin) expressed in baculovirus infected Sf9 cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50334681(((1R)-4-(N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hy...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human full length 11beta-HSD1 assessed as inhibition of conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50514204(CHEMBL4437832)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514215(CHEMBL4577379 | US11274105, Example 4)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514206(CHEMBL4588330 | US11274105, Example 187)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50334680(((1R)-4-(N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hy...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human full length 11beta-HSD1 assessed as inhibition of conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50514214(CHEMBL4542646 | US11274105, Example 41)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50514201(CHEMBL4547370 | US11274105, Example 191)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514203(CHEMBL4593361 | US11274105, Example 6)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50557974(CHEMBL4762294)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of recombinant full length N-terminal polyHis-tagged PI3K p110delta/p85alpha (unknown origin) expressed in baculovirus infected Sf9 cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50334673(CHEMBL1642593 | N-((4S)-4-(3-amino-3-oxopropyl)-4-...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human full length 11beta-HSD1 assessed as inhibition of conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
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