Compile Data Set for Download or QSAR
maximum 50k data
Found 85 with Last Name = 'kneissel' and Initial = 'm'
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308093(1-[3-(2-Hydroxy-ethoxy)-benzyl]-4-(4-isopropyl-phe...)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308090(1-(3-Ethoxy-4-methoxy-benzyl)-4-(4-isopropyl-pheny...)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325523(2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)...)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308081(4-(4-Isopropyl-phenyl)-1-(4-methyl-benzyl)-6-propa...)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308087(4-(4-Isopropyl-phenyl)-1-(3-methyl-benzyl)-6-propa...)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325525(2-((2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyet...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308103(CHEMBL590539 | N-{3-[4-(4-Isopropyl-pheny)-2-oxo-6...)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308108(1-Benzyl-5-cyclopropylmethyl-6-hydroxy-4-(4-isopro...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325524(2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)...)
Affinity DataIC50:  2.60nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308089(1-(3-Methoxy-benzyl)-4-(4-isopropyl-phenyl)-6-prop...)
Affinity DataIC50:  2.70nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308091(CHEMBL597194 | {3-[4-(4-Isopropyl-phenyl)-2-oxo-6-...)
Affinity DataIC50:  3.40nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308106(5-Allyl-1-benzyl-6-hydroxy-4-(4-isopropyl-phenyl)-...)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325522(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325521(2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308082(1-(4-Ethyl-benzyl)-4-(4-isopropyl-phenyl)-6-propar...)
Affinity DataIC50:  4.20nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308084(4-(4-Isopropyl-phenyl)-1-(4-methoxy-benzyl)-6-prop...)
Affinity DataIC50:  4.20nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308080(1-Benzyl-4-(4-isopropyl-phenyl)-6-propargyloxy-1H-...)
Affinity DataIC50:  4.40nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325519(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325515(5-benzyl-4-bromo-2-(4-isopropylphenyl)-7-methoxy-1...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325508(5-bromo-4-iodo-2-(4-isopropylphenyl)-7-methoxy-1-(...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308107(1-Benzyl-6-hydroxy-4-(4-isopropyl-phenyl)-5-propyl...)
Affinity DataIC50:  6.60nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308092(1-[3-(2-Hydroxy-ethoxy)-benzyl]-4-(4-isopropyl-phe...)
Affinity DataIC50:  7.30nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308105(2-[4-(3-Dimethylamino-propyl)piperazin-1-yl]-N-{3-...)
Affinity DataIC50:  8.10nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308078(1-Isopropyl-4-(4-isopropyl-phenyl)-6-propargyloxy-...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325509(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308086(CHEMBL603248 | {4-[4-(4-Isopropyl-phenyl)-2-oxo-6-...)
Affinity DataIC50:  12.6nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308104(CHEMBL590552 | N-{3-[4-(4-Isopropyl-pheny)-2-oxo-6...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325498(4-iodo-2-(4-isopropylphenyl)-7-methoxy-1-(2-methox...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308088(1-(3-Ethyl-benzyl)-4-(4-isopropyl-phenyl)-6-propar...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325507(4,5-dibromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-m...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325520(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325510(5-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308085(1-(4-Ethoxy-benzyl)-4-(4-isopropyl-phenyl)-6-propa...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325497(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325511(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325516(2-(4-isopropylphenyl)-7-methoxy-5-(2-methoxybenzyl...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308083(1-(4-Isopropyl-benzyl)-4-(4-isopropyl-phenyl)-6-pr...)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308100(6-(Propargylamino)-1-isopropyl-4-(4-isopropyl-phen...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325517(4-bromo-5-(3,4-dimethoxybenzyl)-2-(4-isopropylphen...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325496(4-chloro-2-(4-isopropylphenyl)-7-methoxy-1-(2-meth...)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325499(2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325514(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308098(6-Allylamino-1-isopropyl-4-(4-isopropyl-phenyl)-1H...)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308101(6-Dipropargylamino-1-isopropyl-4-(4-isopropyl-phen...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308079(6-But-2-ynyloxy-1-isopropyl-4-(4-isopropyl-phenyl)...)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308076(6-Allyloxy-1-isopropyl-4-(4-isopropyl-phenyl)-1H-q...)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325503(2-(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1H-benz...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325512(4-bromo-5-ethyl-2-(4-isopropylphenyl)-7-methoxy-1-...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50325504(2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)...)
Affinity DataIC50:  210nMAssay Description:Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308099(6-(Allyl-methyl-amino)-1-isopropyl-4-(4-isopropyl-...)
Affinity DataIC50:  230nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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