Affinity DataKi: 0.430nMAssay Description:Binding affinity against human Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.970nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:In vitro inhibitory activity against human Endothelin A receptor using radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory activity of the compound was evaluated in rat liver microsomes using Acyl coenzyme A:cholesterol acyltransferase microsomal assay.More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 574nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of calmodulin-independent form of myosin light chain kinase isolated from chicken gizzard.More data for this Ligand-Target Pair
Affinity DataIC50: 723nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 887nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of native form of chicken MLCK (myosin light chain kinase)More data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of native form of chicken MLCK (myosin light chain kinase)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair