Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant BtkMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant ALK2 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant TNK2 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant LIMK1 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
TargetMacrophage inflammatory protein-1 alpha receptor(Rattus norvegicus)
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Binding affinity at rat CCR1More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Tanabe Research Laboratories
Curated by ChEMBL
Tanabe Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cellsMore data for this Ligand-Target Pair