TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.0420nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.358nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [125I]iodoproxyfan from human full-length histamine H3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 1.12nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 1.21nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 1.44nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 1.54nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]histamine from human full-length histamine H4 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 1.67nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 2.38nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [125I]iodoproxyfan from human full-length histamine H3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [125I]Iodoproxyfan from human histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 2.96nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 3.21nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 3.27nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 3.75nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 4.06nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 4.25nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]histamine from human full-length histamine H4 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 4.56nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 4.90nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]histamine from histamine H3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 7.40nMAssay Description:Displacement of [125I]Iodoproxyfan from human histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]histamine from histamine H3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in CHOK1 cell membranes after 90 minsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor after 45 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 11.2nMAssay Description:Displacement of [125I]Iodoproxyfan from human histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]histamine from histamine H3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]histamine from histamine H3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [125I]Iodoproxyfan from recombinant human histamine H3 receptor expressed in CHOK1 cell membranes after 90 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]histamine from histamine H3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity to rat histamine H3 receptorMore data for this Ligand-Target Pair