Affinity DataKi: 13nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 77nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 119nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 161nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 186nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 393nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 605nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 612nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataKi: 773nMAssay Description:Inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as inhibition constant using Boc-Abu-Tle-Le...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST-tagged human SIK2 autophosphorylation measured after 30 mins in presence of [gamma33P]ATP by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in baculovirus infected Sf9 insect cells using...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ATM in human A549 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation by In-Cell-Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ATM (unknown origin) by FRET assayMore data for this Ligand-Target Pair