Affinity DataKi: 2.70nM ΔG°: -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nM ΔG°: -48.8kJ/mole IC50: 30nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 550nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 670nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 2.33E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 3.25E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 4.15E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.65E+5nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair