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Found 36 with Last Name = 'kuster' and Initial = 'je'
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataKi:  14nMAssay Description:Inhibition of PDGF-stimulated autophosphorylation of PDGF-receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50212379(CHEMBL125462)
Affinity DataIC50:  58nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039650(6,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL280...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039654(7-Chloro-3-pyridin-4-yl-quinoline | CHEMBL86664)
Affinity DataIC50:  300nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039659(6-Methoxy-3-pyridin-4-yl-quinoline | CHEMBL90780)
Affinity DataIC50:  400nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039649(5,6,7-Trimethoxy-3-pyridin-4-yl-quinoline | CHEMBL...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039660(7-Methoxy-3-pyridin-4-yl-quinoline | CHEMBL329622)
Affinity DataIC50:  600nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50212395(CHEMBL123515)
Affinity DataIC50:  900nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50068666(4-(2-{3-[1-Naphthalen-1-yl-meth-(E)-ylidene]-3H-in...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039652(3-Pyridin-4-yl-quinoline-5,7-diol | CHEMBL87083)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039658(3-Pyridin-4-yl-quinoline | CHEMBL89550)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50008029((4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-e...)
Affinity DataIC50:  3.16E+3nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin-H2 D-isomerase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50008029((4-Methoxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-e...)
Affinity DataIC50:  3.50E+3nMAssay Description:Compound was tested for inhibitory activity against prostaglandin synthetase in mouse brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039651(3-Pyridin-4-yl-quinoline-6,7-diol | CHEMBL87084)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039656(3-Pyridin-4-yl-quinolin-7-ol | CHEMBL314811)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p56 lck kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039650(6,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL280...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p56 lck kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039654(7-Chloro-3-pyridin-4-yl-quinoline | CHEMBL86664)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of erbB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039650(6,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL280...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of erbB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039650(6,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL280...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039651(3-Pyridin-4-yl-quinoline-6,7-diol | CHEMBL87084)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of erbB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039654(7-Chloro-3-pyridin-4-yl-quinoline | CHEMBL86664)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039654(7-Chloro-3-pyridin-4-yl-quinoline | CHEMBL86664)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p56 lck kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039651(3-Pyridin-4-yl-quinoline-6,7-diol | CHEMBL87084)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p56 lck kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of erbB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50068669(4-(2-{2-Methyl-3-[1-naphthalen-1-yl-meth-(Z)-ylide...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin-H2 D-isomerase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50286425(4-(2-{3-[1-Phenyl-meth-(E)-ylidene]-3H-inden-1-yl}...)
Affinity DataIC50:  2.00E+4nMAssay Description:Compound was tested for inhibitory activity against prostaglandin synthetase in mouse brain microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50212355(CHEMBL125199)
Affinity DataIC50:  2.80E+4nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039651(3-Pyridin-4-yl-quinoline-6,7-diol | CHEMBL87084)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50212374(CHEMBL129158)
Affinity DataIC50:  4.50E+4nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039657(7-Methoxy-4-methyl-3-pyridin-4-yl-quinoline | CHEM...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039653(6-Methoxy-4-methyl-3-pyridin-4-yl-quinoline | CHEM...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50212356(CHEMBL421470)
Affinity DataIC50:  9.60E+4nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50212372(CHEMBL340686)
Affinity DataIC50:  9.70E+4nMAssay Description:Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails Article