TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 3.10E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 5.10E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 8.00E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 1.45E+5nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 1.47E+5nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:Activity against human P2Y2-GFP expressed in A549 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Activity against human P2Y1-GFP expressed in 1321N1 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Activity against rat P2Y2-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 450nMAssay Description:Activity against human P2Y2-GFP expressed in A549 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 3.60nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Activity against human P2Y1-GFP expressed in 1321N1 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: >7.00E+3nMAssay Description:Activity against rat P2Y2-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Activity against human P2Y1-GFP expressed in 1321N1 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
Affinity DataEC50: 4.5nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Agonist activity at GFP tagged-human P2Y11 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 9.00E+3nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 3.30E+3nMAssay Description:Agonist activity at GFP tagged-human P2Y11 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluoresce...More data for this Ligand-Target Pair