Affinity DataIC50: 0.240nMAssay Description:The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 0.427nMAssay Description:The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 0.584nMAssay Description:The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19nMAssay Description:The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 2.49nMAssay Description:The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 3.48nMAssay Description:The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 6.13nMAssay Description:The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 24.3nMAssay Description:The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 29.5nMAssay Description:The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 8.35E+6nMAssay Description:The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
Affinity DataIC50: 5.21E+7nMAssay Description:The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Tensha Therapeutics
US Patent
Tensha Therapeutics
US Patent
Affinity DataKd: 1.50E+3nMAssay Description:A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain...More data for this Ligand-Target Pair
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Tensha Therapeutics
US Patent
Tensha Therapeutics
US Patent
Affinity DataKd: 430nMAssay Description:A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain...More data for this Ligand-Target Pair
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Tensha Therapeutics
US Patent
Tensha Therapeutics
US Patent
Affinity DataKd: 1.10E+3nMAssay Description:A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain...More data for this Ligand-Target Pair
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Tensha Therapeutics
US Patent
Tensha Therapeutics
US Patent
Affinity DataKd: 1.10E+3nMAssay Description:A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain...More data for this Ligand-Target Pair
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Tensha Therapeutics
US Patent
Tensha Therapeutics
US Patent
Affinity DataKd: 1.90E+3nMAssay Description:A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain...More data for this Ligand-Target Pair
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Tensha Therapeutics
US Patent
Tensha Therapeutics
US Patent
Affinity DataKd: 1.30E+3nMAssay Description:A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain...More data for this Ligand-Target Pair
Affinity DataKd: 3.60E+3nMAssay Description:A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain...More data for this Ligand-Target Pair
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Tensha Therapeutics
US Patent
Tensha Therapeutics
US Patent