Found 66 with Last Name = 'lee' and Initial = 'jxt' TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 0.0560nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Binding affinity to N-terminal His tagged human recombinant JAK2 (1014 to 1132 residues) expressed in Escherichia coli after 300 mins by LC/MS analys...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of C-terminal GST tagged human recombinant HDAC2 (1 to 488 residues) expressed in Baculovirus infected insect cells in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human HDAC10 using fluorogenic peptide from p53 residues 379 to 382 as substrate in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC11 (1 to 347 residues) expressed in Baculovirus infected insect cells in presence of ATPMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human HDAC10 using fluorogenic peptide from p53 residues 379 to 382 as substrate in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of C-terminal GST tagged human recombinant HDAC2 (1 to 488 residues) expressed in Baculovirus infected insect cells in presence of ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Binding affinity to N-terminal His tagged human recombinant JAK2 (1014 to 1132 residues) expressed in Escherichia coli after 60 to 90 mins by LC/MS a...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 188nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 219nMAssay Description:Binding affinity to N-terminal His tagged human recombinant JAK2 (1014 to 1132 residues) expressed in Escherichia coli after 60 to 90 mins by LC/MS a...More data for this Ligand-Target Pair
Affinity DataIC50: 265nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 265nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 306nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC8 (1 to 377 residues) expressed in Baculovirus infected insect cells in presence of ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 436nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 469nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC8 (1 to 377 residues) expressed in Baculovirus infected insect cells in presence of ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 481nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 502nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 569nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 604nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 854nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 865nMAssay Description:Inhibition of human recombinant HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in Baculovirus infected insect ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in Baculovirus infected insect ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
