Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of human carbonic anhydrase 9 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.850nMAssay Description:Effect on plasma amine oxidase (0.1 uM) after 60 min of incubation at pH 7.2More data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of human carbonic anhydrase 9 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant CA12 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant CA9 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant CA9 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant CA9 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of carbonic anhydrase 12 (unknown origin) preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of human carbonic anhydrase 2 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 ADR expressed in HEK293T cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Inhibition of human carbonic anhydrase 9 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human placental cytochrome P450 19A1 androstenedioneMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant CA12 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 7.30nMAssay Description:Inhibition of human carbonic anhydrase 9 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida College Of Medicine
Curated by ChEMBL
University Of Florida College Of Medicine
Curated by ChEMBL
Affinity DataKi: 7.40nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of bovine adrenal cholesterol side chain cleavage(CSCC) cytochrome P450 11A1More data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair