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Found 17 with Last Name = 'louis' and Initial = 'jm'

Protease(Human immunodeficiency virus 1 (HIV-1))
Georgia State University

Curated by ChEMBL

BDBM50498230(CHEMBL3577576)

Ki: 0.00300nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair

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Protease(Human immunodeficiency virus 1 (HIV-1))
Georgia State University

Curated by ChEMBL

BDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)

Ki: 0.00500nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair

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3D Structure (crystal)

Protease(Human immunodeficiency virus 1 (HIV-1))
Georgia State University

Curated by ChEMBL

BDBM50498229(CHEMBL3577575)

Ki: 0.00600nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Georgia State University

BDBM517((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...)

Ki: 0.540nM ΔG°: -52.4kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,G574S](Human immunodeficiency virus type 1)
Georgia State University

BDBM517((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...)

Ki: 0.550nM ΔG°: -52.3kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,L525I](Human immunodeficiency virus type 1)
Georgia State University

BDBM517((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...)

Ki: 1.40nM ΔG°: -50.0kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,L525I](Human immunodeficiency virus type 1)
Georgia State University

BDBM13935((4S)-4-[(2S)-2-{[(2S)-2-[(2S)-2-[(2S)-2-amino-5-ca...)

Ki: 3.5nM ΔG°: -47.8kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,I551V](Human immunodeficiency virus type 1)
Georgia State University

BDBM517((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...)

Ki: 27nM ΔG°: -42.8kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Georgia State University

BDBM13935((4S)-4-[(2S)-2-{[(2S)-2-[(2S)-2-[(2S)-2-amino-5-ca...)

Ki: 75nM ΔG°: -40.3kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,I551V](Human immunodeficiency virus type 1)
Georgia State University

BDBM13935((4S)-4-[(2S)-2-{[(2S)-2-[(2S)-2-[(2S)-2-amino-5-ca...)

Ki: 230nM ΔG°: -37.5kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,G574S](Human immunodeficiency virus type 1)
Georgia State University

BDBM13935((4S)-4-[(2S)-2-{[(2S)-2-[(2S)-2-[(2S)-2-amino-5-ca...)

Ki: 330nM ΔG°: -36.6kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,L525I](Human immunodeficiency virus type 1)
Georgia State University

BDBM13936((2S)-N-[(1S)-4-carbamimidamido-1-carbamoylbutyl]-2...)

Ki: 2.00E+3nM ΔG°: -32.2kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Georgia State University

BDBM13936((2S)-N-[(1S)-4-carbamimidamido-1-carbamoylbutyl]-2...)

Ki: 2.17E+3nM ΔG°: -32.0kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,G574S](Human immunodeficiency virus type 1)
Georgia State University

BDBM13936((2S)-N-[(1S)-4-carbamimidamido-1-carbamoylbutyl]-2...)

Ki: 3.30E+3nM ΔG°: -31.0kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,I551V](Human immunodeficiency virus type 1)
Georgia State University

BDBM13936((2S)-N-[(1S)-4-carbamimidamido-1-carbamoylbutyl]-2...)

Ki: 4.10E+4nM ΔG°: -24.8kJ/molepH: 5.0 T: 2°CAssay Description:The Ki values were obtained from the IC50 values estimated from an inhibitor dose-response curve with the spectroscopic assay and the chromogenic sub...More data for this Ligand-Target Pair

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3D Structure (crystal)

Protease(Human immunodeficiency virus 1 (HIV-1))
Georgia State University

Curated by ChEMBL

BDBM50498229(CHEMBL3577575)

IC50: 1.00E+3nMAssay Description:Inhibition of N-terminal autoprocessing of transframe region-comprising wild type HIV1 protease precursor by SDS-PAGE methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Protease(Human immunodeficiency virus 1 (HIV-1))
Georgia State University

Curated by ChEMBL

BDBM50498230(CHEMBL3577576)

IC50: 1.00E+3nMAssay Description:Inhibition of N-terminal autoprocessing of transframe region-comprising wild type HIV1 protease precursor by SDS-PAGE methodMore data for this Ligand-Target Pair

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