Affinity DataKi: 0.800nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -47.4kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nM ΔG°: -47.1kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.70nM ΔG°: -46.3kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14.7nM ΔG°: -44.7kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 15.9nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 31nM ΔG°: -42.9kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 52nM ΔG°: -41.6kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 70.2nM ΔG°: -40.8kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 72nM ΔG°: -40.8kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 107nM ΔG°: -39.8kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 148nM ΔG°: -39.0kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 170nM ΔG°: -38.6kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: 470nM ΔG°: -36.1kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 570nM ΔG°: -35.6kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 620nM ΔG°: -35.4kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: 903nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: 930nM ΔG°: -34.4kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 1.42E+3nM ΔG°: -33.4kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 1.54E+3nM ΔG°: -33.2kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 1.67E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.29E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nM ΔG°: -32.1kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair