Affinity DataKi: 0.00100nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.00200nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0870nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:In vitro inhibition of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of HCV genotype 1b BK NS3/4A protease A156T mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition constant against human ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Inhibitory constant of the compound against tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of HCV genotype 1b BK NS3/4A protease A156T mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition constant against human ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibitory constant against trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of HCV genotype 1b BK NS3/4A protease A156T mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of HCV genotype 1b BK NS3/4A protease A156T mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Inhibitory constant against human Coagulation factor XaMore data for this Ligand-Target Pair
Affinity DataKi: 0.770nMAssay Description:Inhibitory constant against human Coagulation factor XaMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of HCV genotype 1b BK NS3/4A protease A156T mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.850nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair