Found 61 with Last Name = 'mcmillan' and Initial = 'b' 
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]sulpiride from dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]pirenzepine from muscarinic M1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]AF-DX384 from muscarinic M2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]LTD4 from LTD4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]DAGO from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]RX781094 from alpha2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]LTB4 from LTB4RMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]SQ29548 from thromboxane A2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]citalopram from serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]WIN-from cocaine site of dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 580nMAssay Description:Displacement of [3H]DMI from norepinephrine transporterMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 3.60E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 4.20E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 4.90E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 5.80E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 7.80E+4nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Disruption of human N-terminal SmBiT peptide-tagged PRMT5/ N-terminal LgBiT tagged RIOK1 complex expressed in permeabilized HEK293T cells by NanoBiT ...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Disruption of human N-terminal SmBiT peptide-tagged PRMT5/ N-terminal LgBiT tagged RIOK1 complex expressed in permeabilized HEK293T cells by NanoBiT ...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 1.01E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 1.27E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 1.38E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 1.41E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 1.92E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 2.33E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 3.17E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 3.56E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 5.54E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 7.21E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 7.29E+4nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
