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Found 66 with Last Name = 'mcnamara' and Initial = 'e'
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122730(CHEMBL3623135)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122742(CHEMBL3623139)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597817(CHEMBL5192406)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597812(CHEMBL5192215)
Affinity DataIC50:  3nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597817(CHEMBL5192406)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) preincubated with compound for 20 mins followed by substrate addition measured after 120 mins in presence of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122740(CHEMBL3623137)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122741(CHEMBL3623138)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122739(CHEMBL3623136)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597813(CHEMBL5183804)
Affinity DataIC50:  13nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122729(CHEMBL3623134)
Affinity DataIC50:  15nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122743(CHEMBL3623130)
Affinity DataIC50:  16nMAssay Description:Inhibition of MAP4K4 (unknown origin) by LC3K methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011536(CHEMBL3262587 | US9592235, Example 184 | US9855269...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122685(CHEMBL3623128)
Affinity DataIC50:  18nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597807(CHEMBL5190688)
Affinity DataIC50:  20nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122728(CHEMBL3623133)
Affinity DataIC50:  32nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548269((R)-2-((R)-3-methylmorpholino)-6-(trifluoromethyl)...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122725(CHEMBL3623131)
Affinity DataIC50:  41nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548239((R)-7-(tert-butyl)-2-((R)-3-methylmorpholino)-6,7-...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122688(CHEMBL3623129)
Affinity DataIC50:  46nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597814(CHEMBL5200373)
Affinity DataIC50:  48nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597809(CHEMBL5181274)
Affinity DataIC50:  53nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50:  58nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011560(CHEMBL3262579 | US9592235, Example 187 | US9855269...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011564(CHEMBL3262583 | MAP10 | US9592235, Example 158 | U...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548235((R)-7-isopropyl-2-((R)-3-methylmorpholino)-6,7-dih...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548243((5aS,8aR)-2-((R)-3-methylmorpholino)-5,5a,6,7,8,8a...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548265((R)-7'-cyclopropyl-2'-((R)-3-methylmorpholino)-7'H...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548251((S)-2-((R)-3-methylmorpholino)-7-(trifluoromethyl)...)
Affinity DataIC50:  92nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011551(CHEMBL3262570 | US9592235, Example 268 | US9855269...)
Affinity DataIC50:  121nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597811(CHEMBL5195258)
Affinity DataIC50:  130nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597818(CHEMBL5197817)
Affinity DataIC50:  130nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011568(CHEMBL3262584 | US9592235, Example 186 | US9855269...)
Affinity DataIC50:  132nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548247((S)-7-(2-hydroxypropan-2-yl)-2-((R)-3-methylmorpho...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548253((6S,7R)-7-cyclopropyl-6-methyl-2-((R)-3-methylmorp...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011550(CHEMBL3262569)
Affinity DataIC50:  189nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011556(CHEMBL3262575 | US9592235, Example 164 | US9855269...)
Affinity DataIC50:  225nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548237((R)-7-cyclobutyl-2-((R)-3-methylmorpholino)-6,7-di...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597816(CHEMBL5202968)
Affinity DataIC50:  240nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011562(CHEMBL3262581 | US9592235, Example 163 | US9855269...)
Affinity DataIC50:  297nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597808(CHEMBL5190274)
Affinity DataIC50:  320nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011553(CHEMBL3262572 | US9592235, Example 167 | US9855269...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597818(CHEMBL5197817)
Affinity DataIC50:  330nMAssay Description:Inhibition of PI3Kalpha (unknown origin) preincubated with compound for 20 mins followed by substrate addition measured after 120 mins in presence of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM548241((R)-7-cyclopentyl-2-((R)-3-methylmorpholino)-6,7-d...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011559(CHEMBL3262578 | US9592235, Example 269 | US9855269...)
Affinity DataIC50:  351nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011563(CHEMBL3262582)
Affinity DataIC50:  381nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011558(CHEMBL3262577 | US9592235, Example 266 | US9855269...)
Affinity DataIC50:  387nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50122727(CHEMBL3623132)
Affinity DataIC50:  401nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011555(CHEMBL3262574 | US9592235, Example 162 | US9855269...)
Affinity DataIC50:  423nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50597810(CHEMBL5204287)
Affinity DataIC50:  470nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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