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Found 555 with Last Name = 'meissner' and Initial = 'rs'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391916(CHEMBL2147556)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391923(CHEMBL2147566)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391913(CHEMBL2147553)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391917(CHEMBL2147557)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391919(CHEMBL2147561)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391920(CHEMBL2147562)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391925(CHEMBL2147569)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391924(CHEMBL2147567)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391918(CHEMBL2147558)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391922(CHEMBL2147564)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391914(CHEMBL2147554)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296936(16-[(3-Fluorophenyl)methylidene]-17beta-hydroxy-4-...)
Affinity DataKi:  29nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391921(CHEMBL2147563)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296937(16-[(3,5-Difluorophenyl)methylidene]-17beta-hydrox...)
Affinity DataKi:  46nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391926(CHEMBL2147572)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391915(CHEMBL2147555)
Affinity DataKi:  155nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296938(16-(Phenylmethylidene)-17beta-hydroxy-4-methyl-4-a...)
Affinity DataKi:  225nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296935(16alpha-(3-Fluorobenzyl)-17beta-hydroxy-4-methyl-4...)
Affinity DataKi:  240nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296941(16-(Pyridin-4-ylmethylidene)-17beta-hydroxy-4-meth...)
Affinity DataKi:  320nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391927(CHEMBL2147573)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50391928(CHEMBL2147629)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]-dexamethasone from human full length GR expressed in insect Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296942(16-(Pyridin-3-ylmethylidene)-17beta-hydroxy-4-meth...)
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296944(16-[(2-cyclopropylpyrimidin-5-yl)methylidene]-17be...)
Affinity DataKi:  4.65E+3nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296945(16-[(2-Methoxypyrimidin-5-yl)methylidene]-17beta-h...)
Affinity DataKi:  7.90E+3nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296939(16-(Methylmethylidene)-17beta-hydroxy-4-methyl-4-a...)
Affinity DataKi:  8.05E+3nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296943(16-(Pyrimidin-5-ylmethylidene)-17beta-hydroxy-4-me...)
Affinity DataKi:  9.40E+3nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296946(16-[(2-Methylpyrimidin-5-yl)methylidene]-17beta-hy...)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296933(16alpha-(Methyl)-17beta-hydroxy-4-methyl-4-aza-5al...)
Affinity DataKi:  2.00E+4nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296947(16-{[(2-Methylamino)pyrimidin-5-yl]methylidene}-17...)
Affinity DataKi:  2.25E+4nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296934(16alpha-(Methoxymethyl)-17beta-hydroxy-4-methyl-4-...)
Affinity DataKi:  3.90E+4nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296932((4aR,4bS,6aS,7S,9aS,9bR,11aR)-7-hydroxy-1,4a,6a-tr...)
Affinity DataKi:  1.30E+5nMAssay Description:Binding affinity to human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134778((S)-3-(6-Methoxy-pyridin-3-yl)-3-{2-oxo-3-[3-(5,6,...)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of alphaV-beta3 integrin bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134777((S)-3-(2,3-Dihydro-benzofuran-6-yl)-3-{2-oxo-3-[3-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of alphaV-beta3 integrin bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136246((S)-3-{(R)-2-Oxo-3-[3-(5,6,7,8-tetrahydro-[1,8]nap...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162755((S)-3-(6-Methoxy-pyridin-3-yl)-7-oxo-9-(5,6,7,8-te...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of 2(S)-(4-125-iodo-benzenesulfonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136245((S)-3-(2,3-Dihydro-benzofuran-6-yl)-3-{(S)-2-oxo-3...)
Affinity DataIC50:  0.220nMAssay Description:Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162756((3S,7R)-7-Hydroxy-3-(6-methoxy-pyridin-3-yl)-9-(5,...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of 2(S)-(4-125-iodo-benzenesulfonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162757((3S,7S)-7-Hydroxy-3-(6-methoxy-pyridin-3-yl)-9-(5,...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of 2(S)-(4-125-iodo-benzenesulfonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134780((S)-3-{2-Oxo-3-[3-(5,6,7,8-tetrahydro-[1,8]naphthy...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of alphaV-beta3 integrin bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136244((S)-3-{(S)-2-Oxo-3-[3-(5,6,7,8-tetrahydro-[1,8]nap...)
Affinity DataIC50:  0.25nMAssay Description:Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107397((S)-3-(2-{(S)-2-Oxo-3-[2-(5,6,7,8-tetrahydro-[1,8]...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of rate of ADP-stimulated gel-filtered human platelet aggregation mediated by integrin alphaIIb beta-3 in PLAGGIN assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134776((S)-3-(3-Fluoro-4-methoxy-phenyl)-3-{2-oxo-3-[3-(5...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of alphaV-beta3 integrin bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136247((S)-3-(2,3-Dihydro-benzofuran-6-yl)-3-{(R)-2-oxo-3...)
Affinity DataIC50:  0.390nMAssay Description:Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134779((S)-3-{3-[3-(7-Hydroxy-5,6,7,8-tetrahydro-[1,8]nap...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of alphaV-beta3 integrin bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153030((S)-3-(6-Methoxy-pyridin-3-yl)-9-(5,6,7,8-tetrahyd...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of 2(S)-(4-125-iodo-benzenesulfonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107399((S)-3-(2-{(R)-2-Oxo-3-[2-(5,6,7,8-tetrahydro-[1,8]...)
Affinity DataIC50:  0.940nMAssay Description:Displacement of a non-peptide radioligand from human recombinant alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]methyltrienolone from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107403((S)-3-(2-{2-Oxo-3-[2-(5,6,7,8-tetrahydro-[1,8]naph...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of rate of ADP-stimulated gel-filtered human platelet aggregation mediated by integrin alphaIIb beta-3 in PLAGGIN assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107404((S)-3-Pyridin-3-yl-3-[2-(4-5,6,7,8-tetrahydro-[1,8...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of rate of ADP-stimulated gel-filtered human platelet aggregation mediated by integrin alphaIIb beta-3 in PLAGGIN assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116975((S)-3-Quinolin-3-yl-3-(5-5,6,7,8-tetrahydro-[1,8]n...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [125I]-labeled nonpeptide from purified recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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