Compile Data Set for Download or QSAR
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Found 242 with Last Name = 'metzger' and Initial = 'd'
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50:  0.600nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468133(CHEMBL4278161)
Affinity DataIC50:  0.700nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468133(CHEMBL4278161)
Affinity DataIC50:  0.800nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  0.900nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50322981(CHEMBL1210207 | N-(1-((2,6-diethoxy-4'-fluorobiphe...)
Affinity DataIC50:  1nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  1.20nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50322981(CHEMBL1210207 | N-(1-((2,6-diethoxy-4'-fluorobiphe...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468130(CHEMBL4292255)
Affinity DataIC50:  1.60nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50499290(CHEMBL3734797)
Affinity DataIC50:  2nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  2.10nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468130(CHEMBL4292255)
Affinity DataIC50:  2.5nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468131(CHEMBL4277106)
Affinity DataIC50:  2.5nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50322981(CHEMBL1210207 | N-(1-((2,6-diethoxy-4'-fluorobiphe...)
Affinity DataIC50:  2.70nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468127(CHEMBL4288417)
Affinity DataIC50:  2.70nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50:  2.90nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50499298(CHEMBL3734847)
Affinity DataIC50:  3nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50322981(CHEMBL1210207 | N-(1-((2,6-diethoxy-4'-fluorobiphe...)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50499292(CHEMBL3734764)
Affinity DataIC50:  4nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468131(CHEMBL4277106)
Affinity DataIC50:  4.5nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468131(CHEMBL4277106)
Affinity DataIC50:  6.10nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50348226(CHEMBL1800622)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein using exogenous LDL and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50:  7.10nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468132(CHEMBL4289922)
Affinity DataIC50:  7.40nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468127(CHEMBL4288417)
Affinity DataIC50:  7.60nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468133(CHEMBL4278161)
Affinity DataIC50:  8.60nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578772(CHEMBL4873416)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein using exogenous LDL and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468126(CHEMBL4280531)
Affinity DataIC50:  13nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468134(CHEMBL4281620)
Affinity DataIC50:  13nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578733(CHEMBL4875851)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578733(CHEMBL4875851)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein using exogenous LDL and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468131(CHEMBL4277106)
Affinity DataIC50:  16nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50348228(CHEMBL1800807)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein using exogenous LDL and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM264531((7R)-7-[3,5- bis(trifluoromethyl)phenyl]- 4-{[4'-f...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578756(CHEMBL4876430)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578737(CHEMBL4852134)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468134(CHEMBL4281620)
Affinity DataIC50:  21nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM138247(US8871738, 30)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50499286(CHEMBL3735388)
Affinity DataIC50:  23nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578735(CHEMBL4853626)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50348226(CHEMBL1800622)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578754(CHEMBL4856008)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468126(CHEMBL4280531)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468133(CHEMBL4278161)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578770(CHEMBL4859118)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein using exogenous LDL and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578767(CHEMBL4876714)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein using exogenous LDL and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578742(CHEMBL4854376)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468132(CHEMBL4289922)
Affinity DataIC50:  32nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578736(CHEMBL4852538)
Affinity DataIC50:  34nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50578748(CHEMBL4848688)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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