Compile Data Set for Download or QSAR
maximum 50k data
Found 718 with Last Name = 'miller' and Initial = 'cp'
TargetAndrogen receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336997(2-chloro-4-((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxa...)
Affinity DataKi:  7nMAssay Description:Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataKi:  10nMAssay Description:Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataKi:  29nMAssay Description:Displacement of fluorescent-tagged R1881 from androgen receptor after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112830(US8629167, 41)
Affinity DataIC50:  0.0200nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112818(US8629167, 29)
Affinity DataIC50:  0.0300nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112828(US8629167, 39)
Affinity DataIC50:  0.100nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112829(US8629167, 40)
Affinity DataIC50:  0.200nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112826(US8629167, 37)
Affinity DataIC50:  0.200nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112824(US8629167, 35)
Affinity DataIC50:  0.200nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112819(US8629167, 30)
Affinity DataIC50:  0.300nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152609(7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzofuran-5...)
Affinity DataIC50:  0.350nMAssay Description:Binding affinity for human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112797(US8629167, 7)
Affinity DataIC50:  0.400nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)
Affinity DataIC50:  0.470nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112805(US8629167, 15)
Affinity DataIC50:  0.5nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152616(4-Bromo-2-(4-hydroxy-phenyl)-7-methoxy-benzofuran-...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity for human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112812(US8629167, 23)
Affinity DataIC50:  0.700nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  0.720nMAssay Description:In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiolMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  0.720nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112853(US8629167, 65)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112852(US8629167, 64)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM594883(US11584756, Compound 2 | US11584756, Example S-2)
Affinity DataIC50:  1nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112865(US8629167, 78)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112867(US8629167, 80)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112882(US8629167, 95)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112836(US8629167, 47)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112841(US8629167, 53)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112842(US8629167, 54)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112851(US8629167, 63)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
Radius Health

US Patent
LigandPNGBDBM112849(US8629167, 61)
Affinity DataIC50:  1nMAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152628(2-(3-Fluoro-4-hydroxy-phenyl)-5-hydroxy-benzofuran...)
Affinity DataIC50:  1.10nMAssay Description:Binding affinity for human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM594901(US11584756, Compound 150 | US11584756, Example S-2...)
Affinity DataIC50:  1.20nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor beta(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50166755(5-Hydroxy-2-(4-hydroxy-phenyl)-3-methylsulfanyl-in...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154059(7-Bromo-2-(2-fluoro-4-hydroxy-phenyl)-benzooxazol-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154134(2-(4-Hydroxy-phenyl)-7-propenyl-benzooxazol-5-ol |...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154078(7-Bromo-2-(4-hydroxy-2-methyl-phenyl)-benzooxazol-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154137(3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50152629(7-Bromo-2-(4-hydroxy-phenyl)-benzofuran-5-ol | CHE...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity for human Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099587(2-(4-Hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154048(3-(5-Hydroxy-naphthalen-1-yl)-benzo[d]isoxazol-6-o...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152626(7-Chloro-2-(4-hydroxy-phenyl)-benzofuran-5-ol | CH...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity for human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50130177(2,6,8-Trihydroxy-10,11-dioxa-benzo[b]fluoren-5-one...)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity towards human estrogen receptor beta (ERbeta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50166756(3-Bromo-5-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM594911(US11584756, Compound 159 | US11584756, Example S-3...)
Affinity DataIC50:  1.70nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20731(4-bromo-6-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM594896(US11584756, Compound 147 | US11584756, Example S-1...)
Affinity DataIC50:  1.80nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154140(2-(2-Fluoro-4-hydroxy-phenyl)-7-vinyl-benzooxazol-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 718 total ) | Next | Last >>
Jump to: