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Found 75 with Last Name = 'miret' and Initial = 'jj'
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23222(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of human LDH-AMore data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146014(CHEMBL3765554)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human ChoKalpha using choline as substrate by ultraviolet spectroscopic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145944(CHEMBL3763540)
Affinity DataIC50:  66nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145946(CHEMBL3763931)
Affinity DataIC50:  85nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425797(CHEMBL2316885)
Affinity DataIC50:  120nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145989(CHEMBL3763982)
Affinity DataIC50:  165nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425798(CHEMBL2316886)
Affinity DataIC50:  220nMAssay Description:Inhibition of LDH-A (unknown origin) in absence of 0.1% TritonMore data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145945(CHEMBL3764278)
Affinity DataIC50:  233nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145942(CHEMBL3765239)
Affinity DataIC50:  251nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146003(CHEMBL3763453)
Affinity DataIC50:  255nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145947(CHEMBL3763792)
Affinity DataIC50:  268nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425798(CHEMBL2316886)
Affinity DataIC50:  325nMAssay Description:Inhibition of LDH-A (unknown origin) in presence of 0.1% TritonMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425798(CHEMBL2316886)
Affinity DataIC50:  440nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145943(CHEMBL3763801)
Affinity DataIC50:  457nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145946(CHEMBL3763931)
Affinity DataIC50:  750nMAssay Description:Inhibition of ChoKalpha in human MDA-MB-415 cells assessed as reduction in phosphocholine level after 24 hrs by NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145931(CHEMBL3764898)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145939(CHEMBL3764767)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145930(CHEMBL3763340)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145943(CHEMBL3763801)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of ChoKalpha in human MDA-MB-468 cells assessed as reduction in phosphocholine level after 24 hrs by NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425794(CHEMBL2316883)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425796(CHEMBL2316884)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145940(CHEMBL3765567)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145929(CHEMBL3765650)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145928(CHEMBL3765077)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145934(CHEMBL3764904)
Affinity DataIC50:  4.95E+3nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425793(CHEMBL2316881)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425795(CHEMBL2316882)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145927(CHEMBL3764395)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066974(7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-naphthale...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of LDH-A (unknown origin) in absence of 0.1% TritonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425799(CHEMBL2316888)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145925(CHEMBL3764475)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145921(CHEMBL3763196)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425800(CHEMBL2316887)
Affinity DataIC50:  3.42E+5nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425801(CHEMBL2316891)
Affinity DataIC50:  7.70E+5nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425802(CHEMBL2316889)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145919(CHEMBL3765610)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425804(6-Phenylnicotinic Acid | CHEMBL2316892)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425803(CHEMBL2316893)
Affinity DataIC50:  2.20E+6nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50425792(CHEMBL2316880)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataKd:  1.32E+5nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145919(CHEMBL3765610)
Affinity DataKd:  1.94E+5nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataKd:  4.90E+5nMAssay Description:Binding affinity to carbonic anhydrase2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145921(CHEMBL3763196)
Affinity DataKd:  3.40E+5nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145921(CHEMBL3763196)
Affinity DataKd:  1.40E+6nMAssay Description:Binding affinity to carbonic anhydrase2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145925(CHEMBL3764475)
Affinity DataKd:  6.30E+5nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145925(CHEMBL3764475)
Affinity DataKd:  6.70E+5nMAssay Description:Binding affinity to carbonic anhydrase2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145927(CHEMBL3764395)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145928(CHEMBL3765077)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145929(CHEMBL3765650)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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