TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 261nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged TrkA (440 to end residues) expressed in baculovirus infected Sf21 insect cells using KKKSPGEYV...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human N-terminal His6-tagged MET (974 to end residues) expressed in baculovirus infected Sf21 insect cells using KKKSPGEYVNIEFG as subs...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human N-terminal His6-tagged MSK1 (2 to end residues) expressed in baculovirus infected Sf21 insect cells using Crosstide as substrateMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human N-terminal His6-tagged PDGFRbeta (557 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) ...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length human untagged PKAalpha expressed in Escherichia coli BL21 (DE3) pLysS cells using Kemptide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human full-length N-terminal His6-tagged PKBalpha expressed in baculovirus infected Sf21 insect cells using Crosstide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human N-terminal His6-tagged (2 to end residues) PKCbeta expressed in baculovirus infected Sf21 insect cells using Histone H1 as substr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PKCzetaMore data for this Ligand-Target Pair